WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H130259
CAS#: N/A
Description: YD2160 is the negative control for GD433 and is inactive against NTMT1.
Hodoodo Cat#: H130259
Name: YD2160
CAS#: N/A
Chemical Formula: C18H23N5O2S
Exact Mass: 373.16
Molecular Weight: 373.480
Elemental Analysis: C, 57.89; H, 6.21; N, 18.75; O, 8.57; S, 8.58
This product is not in stock, which may be available by custom synthesis.
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Synonym: YD2160; YD 2160; YD-2160
IUPAC/Chemical Name: (S)-quinuclidin-3-yl (2-(2-(pyrimidin-5-yl)thiazol-4-yl)propan-2-yl)carbamate
InChi Key: NSGIQFLCKPHRDC-CQSZACIVSA-N
InChi Code: InChI=1S/C18H23N5O2S/c1-18(2,15-10-26-16(21-15)13-7-19-11-20-8-13)22-17(24)25-14-9-23-5-3-12(14)4-6-23/h7-8,10-12,14H,3-6,9H2,1-2H3,(H,22,24)/t14-/m1/s1
SMILES Code: O=C(O[C@@H]1CN2CCC1CC2)NC(C)(C3=CSC(C4=CN=CN=C4)=N3)C
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 373.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1. Deng Y, Dong G, Meng Y, Noinaj N, Huang R. Structure-Activity Relationship Studies of Venglustat on NTMT1 Inhibition. J Med Chem. 2023 Jan 26;66(2):1601-1615. doi: 10.1021/acs.jmedchem.2c01854. Epub 2023 Jan 12. PMID: 36634151; PMCID: PMC9892271.