WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H461034
CAS#: 76034-18-9
Description: 13-Deoxycarminomycin is an antitumor antibiotic.
Hodoodo Cat#: H461034
Name: 13-Deoxycarminomycin
CAS#: 76034-18-9
Chemical Formula: C26H29NO9
Exact Mass: 499.18
Molecular Weight: 499.510
Elemental Analysis: C, 62.52; H, 5.85; N, 2.80; O, 28.83
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Synonym: 13-Deoxycarminomycin; Antibiotic D 788-11; R 20X; R-20X; R20X;
IUPAC/Chemical Name: (8S,10S)-10-(((4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-8-ethyl-1,6,8,11-tetrahydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione
InChi Key: UHYFCDBUKBJSFA-IZLYCFEBSA-N
InChi Code: InChI=1S/C26H29NO9/c1-3-26(34)8-12-18(15(9-26)36-16-7-13(27)21(29)10(2)35-16)25(33)20-19(23(12)31)22(30)11-5-4-6-14(28)17(11)24(20)32/h4-6,10,13,15-16,21,28-29,31,33-34H,3,7-9,27H2,1-2H3/t10-,13-,15-,16?,21+,26-/m0/s1
SMILES Code: CC[C@]1(C[C@@H](c2c(C1)c(O)c3c(C(c4c(C3=O)cccc4O)=O)c2O)OC5C[C@@H]([C@@H]([C@@H](O5)C)O)N)O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
More Info:
Biological target: | |
In vitro activity: | |
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The following data is based on the product molecular weight 499.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Cassinelli G, Forenza S, Rivola G, Arcamone F, Grein A, Merli S, Casazza AM. 13-Deoxycarminomycin, a new biosynthetic anthracycline. J Nat Prod. 1985 May-Jun;48(3):435-9. PubMed PMID: 3861771.
2: Dickens ML, Priestley ND, Strohl WR. In vivo and in vitro bioconversion of epsilon-rhodomycinone glycoside to doxorubicin: functions of DauP, DauK, and DoxA. J Bacteriol. 1997 Apr;179(8):2641-50. PubMed PMID: 9098063; PubMed Central PMCID: PMC179014.