WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H592303
CAS#: 120-89-8
Description: Parabanic acid is the singlet oxygen specific oxidation product of uric acid.
Hodoodo Cat#: H592303
Name: Parabanic acid
CAS#: 120-89-8
Chemical Formula: C3H2N2O3
Exact Mass: 114.01
Molecular Weight: 114.060
Elemental Analysis: C, 31.59; H, 1.77; N, 24.56; O, 42.08
Synonym: Parabanic acid; NSC 9789; NSC-9789; NSC9789
IUPAC/Chemical Name: 2,4,5-Imidazolidinetrione
InChi Key: ZFLIKDUSUDBGCD-UHFFFAOYSA-N
InChi Code: InChI=1S/C3H2N2O3/c6-1-2(7)5-3(8)4-1/h(H2,4,5,6,7,8)
SMILES Code: O=C1NC(C(N1)=O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 114.06 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Iida S, Ohkubo Y, Yamamoto Y, Fujisawa A. Parabanic acid is the singlet oxygen specific oxidation product of uric acid. J Clin Biochem Nutr. 2017 Nov;61(3):169-175. doi: 10.3164/jcbn.17-24. Epub 2017 Sep 5. PubMed PMID: 29203957; PubMed Central PMCID: PMC5703782.
2: Dávalos JZ, Ribeiro da Silva Md, Ribeiro da Silva MA, Freitas VL, Jiménez P, Roux MV, Cabildo P, Claramunt RM, Elguero J. Computational thermochemistry of six ureas, imidazolidin-2-one, N,N'-trimethyleneurea, benzimidazolinone, parabanic acid, barbital (5,5'-diethylbarbituric acid), and 3,4,4'-trichlorocarbanilide, with an extension to related compounds. J Phys Chem A. 2010 Sep 2;114(34):9237-45. doi: 10.1021/jp103514f. PubMed PMID: 20681553.
3: Hudson MR, Allis DG, Hudson BS. The vibrational spectrum of parabanic acid by inelastic neutron scattering spectroscopy and simulation by solid-state DFT. J Phys Chem A. 2010 Mar 18;114(10):3630-41. doi: 10.1021/jp9114095. PubMed PMID: 20166734.
4: Hillered L, Persson L. Parabanic acid for monitoring of oxygen radical activity in the injured human brain. Neuroreport. 1995 Sep 11;6(13):1816-20. PubMed PMID: 8541489.