Acamprosate Calcium

CAT#: H326701

CAS#: 77337-73-6


Description: Acamprosate is a medication used along with counselling in the treatment of alcohol dependence. Acamprosate is thought to stabilize the chemical balance in the brain that would otherwise be disrupted by alcohol withdrawal. Reports indicate that acamprosate works to best advantage in combination with psychosocial support and can help facilitate reduced consumption as well as full abstinence. Until it became a generic in the United States, Campral was manufactured and marketed in the United States by Forest Laboratories, while Merck KGaA markets it outside the US.

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Synthetic Routes

Acamprosate Calcium - Synthetic Route 1

Acamprosate Calcium route01

Synthetic reference

Gurjar, Mukund Keshav; Maikap, Golakchandra Sudarshan; Chavan, Anil Bhausaheb; Kadam, Pramod Nanasaheb; Jadhav, Balasaheb Tukaram; Jadhav, Shashishekhar Kailash; Mehta, Samit Satish. A process for the preparation of acamprosate calcium. Assignee Emcure Pharmaceutical Limited, India. 2014.

Acamprosate Calcium - Synthetic Route 2

Acamprosate Calcium route02

Synthetic reference

Cao, Zhihua. Process for preparation of high-purity calcium acamprosate. Assignee Beijing Huaxipharm Co., Ltd. 2009.