Organic Chemistry Acronyms

 

Note: The information shown in the web page was reproduced based on below web page:

https://pubs.rsc.org/en/content/chapterhtml/2014/9781849739962-fp009?isbn=978-1-84973-996-2

https://www.chem.wisc.edu/areas/reich/handouts/acronyms.pdf

https://www.periodni.com/abbreviations_of_chemicals.html

https://www.ch.ic.ac.uk/local/organic/tutorial/Abbreviations.pdf

 

12-crown-4 = 1,4,7,10-Tetraoxacyclodecane

12-Crown-4 1,4,7,10-Tetraoxacycododecane

15-crown-5 = 1,4,7,10,13-Pentaoxacyclopentadecane

18-crown-6 = 1,4,7,10,13,16-Hexaoxacyclooctadecane

9-BBN = 9-Borabicyclononane

9-BBN-H 9-Borabicyclo[3.3.1]nonane

Ac = Acetyl

Ac Acetyl (CH3C=O)

Ac2O = Acetic anhydride

acac Acetylacetonate (ligand)

AcO = Acetate

AIBN = a,a’-Azoisobyronitrile

AIBN Azobis(isobutyronitrile)–radical initiator

All = Allyl

Alloc = Allyloxycarbonyl

Ar = Aryl

bda Benzylidene Acetone

BHT = tert-Butylhydroxytoluene

BHT Butylated hydroxy toluene (2,6-di-t-butyl-4-methylphenol)

BINALH Lithium 2,2′-dihydroxy-1,1′-binaphthylethoxyaluminum hydride

BINAP = 2,2′-Bis(diphenylphosphino)-1,1′-binaphthyl

BINAP 2,2′-Bis(diphenylphosphino)-1,1′-binaphthyl

bipy (bpy) 2,2′-bipyridyl

BMS = Borane-methylsulphide complex

BMS Borane Dimethyl Sulfide

Bn = Benzyl

Bn Benzyl

Boc = tert-Butoxycarbonyl

Boc t-Butyloxycarbonyl (COtC4H9)

BOM = Benzyloxymethyl

BOM Benzyloxymethyl (PhCH2OCH2-alcohol protection)

BOP = Bis(2-oxo-3-oxazolidinyl)phosphine

Bs Brosylate (p-BrC6H4SO2)

BSA = N,O-Bis(trimethylsilyl)acetamide

BSA O, N-Bistrimethylsilyl Acetamide

BTAF = Benzyltrimethylammonium fluoride

BTAF Benzyltrimethylammonium Fluoride

BTMSA = Bis(trimethylsilyl)acetylene

Bu or n-Bu = n-Butyl

Bz = Benzoyl

Bz Benzoyl (caution: sometimes used for benzyl)

Bzl = Benzyl

CAN = Ceric ammonium nitrate

CAN Ceric Ammonium Nitrate

CBS = Corey-Bashki-Shibat

Cbz = Benzyloxycarbonyl

Cbz Carbobenzyloxy (BnOC=O)

Cod = Cyclooctadiene

cod Cyclooctadiene

COT Cyclooctatetraene

Cp = Cyclopentadienyl

Cp Cyclopentadienyl

Cp* Pentamethylcyclopentadienyl

CSA = Camphorsulphonic acid

CSA Camphorsulfonic Acid

CSI Chlorosulfonyl Isocyanate

CTAB Cetyltrimethylammonium bromide

DA Diels-Alder Reaction

DABCO = 1,4-Diazabicyclo[2.2.2]octane, Triethylendiamine

DABCO 1,4-Diazabicyclo[2.2.2]octane

DAST (Diethylamino)sulfur trifluoride Et2NSF3

DAST = Diethylaminosulphur trifluoride

dba = Dibenzylideneacetone

dba Dibenzylideneacetone

DBAD = Di-tert-butyl azodicarboxylate

DBN = 1,5-Diazabyciclo[4.3.0]non-5-ene

DBN 1,5-Diazabicyclo[4.3.0]non-5-ene

DBU = 1,8-Diazabyciclo[5.4.0]undec-7-ene

DBU 1,8-Diazabicyclo[5.4.0]undec-7-ene

DCA 1,9-Dicyanoanthracene

DCC = 1,3-Dicyclohexylcarbodiimide

DCC Dicyclohexyl Carbodiimide

DCM = Dichloromethane

Ddpb = 1,4-bis(diphenylphosphino)butane

DDQ = 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone

DDQ 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone

DDT 1,1-Bis(p-chlorophenyl)-2,2,2-trichloroethane

de Diastereomeric excess

DEAD = Diethyl azodicarboxylate

DEAD(CAT) Diethyl Azodicarboxylate

DET Diethyl Tartrate

DHP = Dihydropiran

DHP Dihydropyran (alcohol protection)

DHP Dihydropyran (O-protection)

DHQD = Dihydroquinidine

DIBAL (DIBAH) Diisobutylaluminum Hydride

DIBAL = Diisobutylaluminium hydride

DIBAL-H = Diisobutylaluminium hydride

DIC = Diisopropylcarbodiimide

Diglyme Diethylene glycol dimethyl ether

Dimsyl Methylsulfinylmethide (MeS(O)CH2

DIOP

DIPEA = Diisopropylethylamine

diphos (dppe) 1,2-Bis(diphenylphosphino)ethane

DIPT Diisopropyl tartrate

DMA = N,N-Dimethylacetamide

DMAC = N,N-Dimethylacetamide

DMAc N,N-Dimethylacetamide (solvent)

DMAD Dimethyl Acetylenedicarboxylate

DMAP = 4-Dimethylaminopyridine

DMAP 4-Dimethylaminopyridine (base catalyst)

DMDO = 2,2-dimethyldioxirane

DMDO Dimethyldioxirane

DME = 1,2-Dimethoxyethane

DME 1,2-Dimethoxyethane (glyme, solvent)

DMF = N,N-Dimethylformamide

DMF Dimethylformamide (solvent)

DMP = Dess-Martin periodinane

DMP Dess-Martin Periodinane

DMPM = 3,4-Dimethoxybenzyl

DMPU = 1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pirimidone

DMPU N,N’-Dimethyl-N,N’-propylene urea

DMS = Dimethylsulphide

DMSO = Dimethylsulphoxide

DMSO Dimethyl Sulfoxide (solvent)

DMSO2 Dimethyl Sulfone

DMTSF Dimethyl(methylthio)sulfonium tetrafluoroborate

DNP Dinitrophenylhydrazine

DNPBA 2,4-Dinitroperbenzoic acid

DPA = Diisopropylamine

DPPA = Diphenylphosphoryl azide

dppb 1,4-Bis(diphenylphosphino)butane

dppe (diphos) 1,2-Bis(diphenylphosphino)ethane

Dppe = 1,2-bis(diphenylphosphino)ethane

dppf Bis(diphenylphosphino)ferrocene

Dppm = Bis(diphenylphosphino)methane

dppp = 1,3-bis(diphenylphosphino)propane

dppp 1,3-Bis(diphenylphosphino)propane

E Entgegen (opposite, trans)

E Methoxycarbonyl CO2CH3

EDC = 1-Ethyl-3-(3-dimethylaminopropy)carbodiimide

EDCI = 1-Ethyl-3-(3-dimethylaminopropy)carbodiimide

EDCI Ethyl Dimethylaminopropyl Carbodiimide

EDTA = Ethylenediaminetetraacetic acid

EDTA Ethylenediaminetetraacetic acid

EE = Ethoxyethyl

EE 1-Ethoxyethoxy (alcohol protection)

ee Enantiomeric Excess

en Ethylene Diamine

EOM = Ethoxymethyl

Et2O = Diethyl ether

FC Friedel-Crafts Reaction

FMOC = 9-Fluorenylmethoxycarbonyl

Fmoc 9-Fluorenylmethoxycarbonyl

Fp Cyclopentadienyldicarbonylferrate

Galvinoxyl Radical trap

Glyme 1,2-Dimethoxyethane

HATU

HBT Hydroxybenzotriazole

hexamethylphosporamide

HMDS = Hexamethyldisilazane

HMDS Hexamethyldisilazide (Me3Si)2NH

HMPA = Hexamethylphosphoramide

HMPA,HMPT Hexamethylphosphorictriamide (solvent, cosolvent)

HMPT = Hexamethylphosphorous triamide

HOAt = 7-Aza-1-hydroxybenzotriazole

HOBt = 1-Hydroxybenzotriazole

HOBT Hydroxybenzotriazole

HSAB Hard-Acid-Soft-Base

hydrochloride

IBX o-Iodoxybenzoic acid

Im = Imidazole

Im Imidazolyl

IPA = Isopropyl alcohol

Ipc = Isopinocampheyl

Ipc2BH Bisisopinocampheylborane

i-Pr or iPr = iso-propilo

KDA = Potassium diisopropylamide

KDA Potassium Diisopropylamide

KHMDS = Potassium bis(trimethylsilyl)amide

LAH = Lithium aluminium hydride

LAH Lithium Aluminum Hydride (LiAlH4)

LDA = Lithium diisopropylamide

LDEA = Lithium diethylamide

LFER Linear Free Energy Relationship

LHMDS = Lithium bis(trimethylsilyl)amide

LHMDS Lithium Hexamethyldisilazide (LiN(SiMe3)2)

LICA Lithium N-isopropylcyclohexylamide

LICKOR Lithium-potassium alkoxide reagents

LIDBB Lithium 4,4′-di-t-butylbiphenylide

Lithium N,N-Dimethylaminonaphthalenide

LiTMP Lithium Tetramethylpiperidide

LTA Lead Tetraacetate (Pb(OAc)4)

MA Maleic Anhydride

Mander Reag

MCPBA = meta-chloroperoxybenzoic acid

MCPBA meta-Chloroperoxybenzoic Acid

Me = Methyl

MEM $-Methoxyethoxymethyl (CH3OCH2CH2O-CH2-)

MEM = 2-Methoxyethoxymethyl

Mes Mesityl (2,4,6-trimethylphenyl)

MOM = Methoxymethyl

MOM Methoxymethyl (CH3OCH2-, alcohol protection).

MoOPH MoO5@Py@HMPA (oxidizing agent)

MOoPHM = Oxodiperoxymolybdenum(pyridine)

MPM = p-Methoxybenzyl

Ms = Methanesulphonyl

MS = Molecular sieves

Ms Methanesulfonyl (Mesyl, CH3SO2)

MTBE = Methyl tert-butyl ether

MTM = Methylthiomethyl

MTM Methylthiomethyl CH3-S-CH2- (alcohol protection)

MTPA “-Methoxy-“-trifluoromethylphenylacetic acid (Mosher)

MVK Methyl Vinyl Ketone (3-Butene-2-one)

NaHMDS = Sodium bis(trimethylsilyl)amide

NBA N-Bromoacetamide

NBS = N-Bromosuccinimide

NBS, NCS N-Bromo, N-Chlorosuccinimide

NCS = N-Chlorosuccinimide

Nf Nonaflate (C4F9SO2)

NIS = N-Iodosuccinimide

NIS N-Iodosuccinimide

NMM = N-Methylmorpholine

NMO = N-Methylmorpholine-N-oxide

NMO N-Methylmorpholine-N-oxide

NMP = N-Methylpyrrolidone

NMP N-Methylpyrrolidone; solvent

n-Pr = n-Propyl

Ns = p-Nitrophenylsulphonyl

Ns p-Nitrobenzenesulfonyl

o-Tol = o-Toluyl

PBB, PCB Polybrominated, Polychlorinated Biphenyls

PCC = Pyridinium chlorochromate

PCC Pyridinium chlorochromate

PDC = Pyridinium dichlorochromate

PDC Pyridinium dichromate

PG Prostaglandins

Ph = Phenyl

phen 1,10-Phenanthroline

PhthN Phthalimido

Piv = Pivaloyl, 2,2-dimethylacetyl

Piv Pivaloyl

PMB = p-Methoxybenzyl

PMB p-Methoxybenzyl

PMDTA N,N,N’,N”,N”-pentamethyldiethylenetriamine

PMP = p-Methoxyphenyl

PMP p-Methoxyphenyl

PNB para-Nitrobenzoate

PPA = Polyphosphoric acid

PPA Polyphosphoric Acid

PPTS = Pyridinium p-toluensulphonate

PPTS Pyridinium p-Toluenesulfonate

Pr = Propyl

PTAD N-Phenyl-1,2,4-triazolinedione

PTC = Phase transfer catalyst

PTC Phase Transfer Catalyst

PTSA = p-Toluenesulphonic acid

p-TsOH = p-Toluenesulphonic acid

Pv = Pivaloyl, 2,2-dimethylacetyl

Py = Pyridine

Py Pyridine; Solvent, base, catalyst

Red-Al® = Sodium bis(2-methoxyethoxy)aluminium hydride

RT Room Temperature

s-Bu or sBu = sec-Butyl

SEM = 2-(Trimethylsilyl)ethoxymethyl

SEM 2-Trimethylsilylethoxymethoxy (alcohol protection)

SES Trimethylsilylethylsulfonyl (amine prot. SO2CH2CH2SiMe3)

Sia2BH Disiamylborane (Me2CHMeCH)2BH

TASF Tris(dimethylamino)sulfonium difluorotrimethylsilicate

TBAF = Tetrabutylammonium fluoride

TBAF Tetra-n-butylammonium fluoride

TBDMS = tert-Butyldimethylsilyl

TBDMS t-Butyldimethylsilyl (alcohol protection)

TBDPS = tert-Butyldiphenylsilyl

TBDPS t-Butyldiphenylsilyl (alcohol protection)

TBHP = tert-Butylhydroperoxyde

TBHP t-Butylhydroperoxide

TBS = tert-Butyldimethylsilyl

TBS t-Butyldimethylsilyl (also TBDMS)

t-Bu or tBu = tert-Butyl

TCDI = Thiocarbonyl diimidazole

TCE 2,2,2-Trichloroethyl (alcohol, acid protection)

TCNE Tetracyanoethylene

TCNQ 7,7,8,8-Tetracyanoquinodimethane

TDAP = Tris(dimethylamino)phosphine

TEA = Triethylamine

TEA Triethylamine

TEBA = Triethylbenzylammonium chloride

TEBAC = Triethylbenzylammonium chloride

Tebbe

TEMPO Tetramethylpiperidinyloxy

TES = Triethylsilyl

TES Triethylsilyl

TESH = Triethylsilane

Tetrahydrofuran; solvent

Tf = Trifluoromethanesulfonyl

Tf Triflate (CF3SO2)

Tf2O = Trifluoromethanesulfonyl anhydride

TFA = Trifluoroacetic acid

TFA Trifluoroacetic(yl)

TFAA = Trifluoroacetic anhydride

TfO = Trifluoromethanesulfonate

TfOH = Trifluoromethanesulfonic acid

Thexyl = 2,3-dimethyl-2-butyl

Thexyl Me2CHMe2CTHF

THF = Tetrahydrofurane

THP = Tetrahydropyranyl

THP Tetrahydropyran (alcohol protecting group)

TIPS = Triisopropylsilyl

TIPS Triisopropylsilyl (alcohol protection)

TMEDA = N,N,N’,N’-Tetramethylethylendiamine

TMEDA N,N,N’,N’-Tetramethylethylenediamine

TMG = Tetramethylguanidine

TMS = Tetramethylsilane

TMS = Trimethylsilyl

TMS Tetramethylsilane, also Trimethylsilyl

TMSI Trimethylsilyl Iodide

TMTAN 1,4,7-trimethyl-1,4,7-tetraazanonane

Tol = p-Toluyl

Tol p-Tolyl

TOSMIC p-Toluenesulfonylmethylisocyanide

TPAP = Tetra-n-propylammonium perruthenate

TPAP Tetra-n-propylammonium Perruthenate

TPP meso-Tetraphenylporphyrin

TPS = Tripropylsilyl

Tr = Trityl, triphenylmethyl

TRIS Tris(hydroxymethyl)aminomethane (buffer)

Trityl Triphenylmethyl

Troc = 2,2,2-Trichloroethoxycarbonyl

Troc Trichloroethyloxycarbonyl (CCl3CH2OC(O)-)

Trt = Trityl, triphenylmethyl

Ts = p-Toluenesulphonyl

Ts Tosyl (p-CH3C6H4SO2)

TTN Thallium Trinitrate

Vitride® = Sodium bis(2-methoxyethoxy)aluminium hydride

WK Wolff-Kishner Reduction

Z = Benzyloxycarbonyl

Z Zusammen (together, cis)

Amino Acids

Proteinogenic Amino Acids

Ala

Alanine

A

Arg

Arginine

R

Asn

Asparagine

N

Asp

Aspartic acid

D

Asx

Asn or Asp

 

Cys

Cysteine

C

Gln

Glutamine

Q

Glu

Glutamic acid

E

Glx

Gln or Glu

 

Gly

Glycine

G

His

Histidine

H

Ile

Isoleucine

I

Leu

Leucine

L

Lys

Lysine

K

Met

Methionine

M

Phe

Phenylalanine

F

Pro

Proline

P

Ser

Serine

S

Thr

Threonine

T

Trp

Tryptophan

W

Tyr

Tyrosine

Y

Val

Valine

V

 

Dha

Dehydroalanine (also ΔAla)

Gla

γ-Carboxyglutamic acid

Glp

pyroglutamic acid; 5-oxoproline (also pGlu)

Hph

Homophenylalanine (Hse=homoserine, and so on). Caution is necessary over the use of the prefix homo in relation to α-amino-acid names and the symbols for homo-analogues. When the term first became current, it was applied to analogues in which a side-chain CH2 extension had been introduced. Thus homoserine has a side-chain CH2CH2OH, homoarginine CH2CH2CH2NHC(NH)NH2, and so on. In such cases, the convention is that a new three-letter symbol for the analogue is derived from the parent, by taking H for homo and combining it with the first two characters of the parental symbol  hence, Hse, Har and so on. Now, however, there is a considerable literature on β-amino acids which are analogues of α-amino acids in which a CH2 group has been inserted between the α-carbon and carboxyl group. These analogues have also been called homo-analogues, and there are instances for example not only of ‘homophenylalanine’, NH2CH(CH2CH2Ph)CO2H, abbreviated Hph, but also ‘homophenylalanine’, NH2CH(CH2Ph)CH2CO2H abbreviated Hph.

Further, members of the analogue class with CH2 interpolated between the α-carbon and the carboxyl group of the parent α-amino acid structure have been called both ‘α-homo’- and ‘β-homo’. Clearly great care is essential, and abbreviations for ‘homo’ analogues ought to be fully defined on every occasion. The term ‘β-homo’ seems preferable for backbone extension (emphasizing as it does that the residue has become a β-amino acid residue), with abbreviated symbolism as illustrated by βHph for NH2CH(CH2Ph)CH2CO2H.

Hyl

δ-Hydroxylysine

Hyp

4-Hydroxyproline

αIle

allo-Isoleucine; 2S, 3R in the L-series

Lan

Lanthionine; S-(2-amino-2-carboxyethyl)cysteine

MeAla

N-Methylalanine (MeVal=N-methylvaline, and so on). This style should not be used for α-methyl residues, for which either a separate unique symbol (such as Aib for α-methylalanine) should be used, or the position of the methyl group should be made explicit as in αMeTyr for α-methyltyrosine.

Nle

Norleucine; α-aminocaproic acid

Orn

Ornithine; 2,5-diaminopentanoic acid

Phg

Phenylglycine; 2-aminophenylacetic acid

Pip

Pipecolic acid; piperidine-s-carboxylic acid

Sar

Sarcosine; N-methylglycine

Sta

Statine; (3S, 4S)-4-amino-3-hydroxy-6-methyl-heptanoic acid

Thi

β-Thienylalanine

Tic

1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid

αThr

allo-Threonine; 2S, 3S in the L-series

Thz

Thiazolidine-4-carboxylic acid, thiaproline

Xaa

Unknown or unspecified (also Aaa)

 

 

Substituents and Protecting Groups

Ac

Acetyl

Acm

Acetamidomethyl

Adoc

1-Adamantyloxycarbonyl

Alloc

Allyloxycarbonyl

Boc

t-Butoxycarbonyl

Bom

π-Benzyloxymethyl

Bpoc

2-(4-Biphenylyl)isopropoxycarbonyl

Btm

Benzylthiomethyl

Bum

π-t-Butoxymethyl

Bui

i-Butyl

Bun

n-Butyl

But

t-Butyl

Bz

Benzoyl

Bzl

Benzyl (also Bn); Bzl(OMe)=4-methoxybenzyl and so on

Cha

Cyclohexylammonium salt

Clt

2-Chlorotrityl

Dcha

Dicyclohexylammonium salt

Dde

1-(4,4-Dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl

Ddz

2-(3,5-Dimethoxyphenyl)-isopropoxycarbonyl

Dnp

2,4-Dinitrophenyl

Dpp

Diphenylphosphinyl

Et

Ethyl

Fmoc

9-Fluorenylmethoxycarbonyl

For

Formyl

Mbh

4,4′-Dimethoxydiphenylmethyl, 4,4′-Dimethoxybenzhydryl

Mbs

4-Methoxybenzenesulphonyl

Me

Methyl

Mob

4-Methoxybenzyl

Mtr

2,3,6-Trimethyl,4-methoxybenzenesulphonyl

Nps

2-Nitrophenylsulphenyl

OA11

Allyl ester

OBt

1-Benzotriazolyl ester

OcHx

Cyclohexyl ester

ONp

4-Nitrophenyl ester

OPcp

Pentachlorophenyl ester

OPfp

Pentafluorophenyl ester

OSu

Succinimido ester

OTce

2,2,2-Trichloroethyl ester

OTcp

2,4,5-Trichlorophenyl ester

Tmob

2,4,5-Trimethoxybenzyl

Mtt

4-Methyltrityl

Pac

Phenacyl, PhCOCH2 (care! Pac also=PhCH2CO)

Ph

Phenyl

Pht

Phthaloyl

Scm

Methoxycarbonylsulphenyl

Pmc

2,2,5,7,8-Pentamethylchroman-6-sulphonyl

Pri

i-Propyl

Prn

n-Propyl

Tfa

Trifluoroacetyl

Tos

4-Toluenesulphonyl (also Ts)

Troc

2,2,2-Trichloroethoxycarbonyl

Trt

Trityl, triphenylmethyl

Xan

9-Xanthydryl

Z

Benzyloxycarbonyl (also Cbz). Z(2C1)=2-chlorobenzyloxycarbonyl and so on

Amino Acid Derivatives

DKP

Diketopiperazine

NCA

N-Carboxyanhydride

PTH

Phenylthiohydantoin

UNCA

Urethane N-carboxyanhydride

Reagents and Solvents

BOP

1-Benzotriazolyloxy-tris-dimethylamino-phosphonium hexafluorophosphate

CDI

Carbonyldiimidazole

DBU

Diazabicyclo[5.4.0]-undec-7-ene

DCCI

Dicyclohexylcarbodiimide (also DCC)

DCHU

Dicyclohexylurea (also DCU)

DCM

Dichloromethane

DEAD

Diethyl azodicarboxylate (DMAD=the dimethyl analogue)

DIPCI

Diisopropylcarbodiimide (also DIC)

DIPEA

Diisopropylethylamine (also DIEA)

DMA

Dimethylacetamide

DMAP

4-Dimethylaminopyridine

DMF

Dimethylformamide

DMS

Dimethylsulphide

DMSO

Dimethylsulphoxide

DPAA

Diphenylphosphoryl azide

EEDQ

2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline

HATU

This is the acronym for the ‘uronium’ coupling reagent derived from HOAt, which was originally thought to have the structure 8, the Hexafluorophosphate salt of the O-(7-Azabenzotriazol-lyl)-Tetramethyl Uronium cation.  In fact this reagent has the isomeric N-oxide structure 9 in the crystalline state, the unwieldy correct name of which does not conform logically with the acronym, but the acronym continues in use.  Similarly, the corresponding reagent derived from HOBt has the firmly attached label HBTU (the tetrafluoroborate salt is also used: TBTU), despite the fact that it is not actually a uronium salt.

HMP

Hexamethylphosphoric triamide (also HMPA, HMPTA)

HOAt

1-Hydroxy-7-azabenzotriazole

HOBt

1-Hydroxybenzotriazole

HOCt

1-Hydroxy-4-ethoxycarbonyl-1,2,3-triazole

NDMBA

N,N′-Dimethylbarbituric acid

NMM

N-Methylmorpholine

PAM

Phenylacetamidomethyl resin

PEG

Polyethylene glycol

PtBOP

1-Benzotriazolyloxy-tris-pyrrolidinophosphonium hexafluorophosphate

SDS

Sodium dodecyl sulphate

TBAF

Tetrabutylammonium fluoride

TBTU

See remarks under HATU above

TEA

Triethylamine

TFA

Trifluoroacetic acid

TFE

Trifluoroethanol

TFMSA

Trifluoromethanesulphonic acid

THF

Tetrahydrofuran

WSCI

Water soluble carbodiimide: 1-ethyl-3-(3′-dimethylaminopropyl)-carbodiimide hydrochloride (also EDC)

Techniques

CD

Circular dichroism

COSY

Correlated spectroscopy

CZE

Capillary zone electrophoresis

ELISA

Enzyme-linked immunosorbent assay

ESI

Electrospray ionization

ESR

Electron spin resonance

FAB

Fast atom bombardment

FT

Fourier transform

GLC

Gas liquid chromatography

hplc

High performance liquid chromatography

IR

Infra red

MALDI

Matrix-assisted laser desorption ionization

MS

Mass spectrometry

NMR

Nuclear magnetic resonance

nOe

Nuclear Overhauser effect

NOESY

Nuclear Overhauser enhanced spectroscopy

ORD

Optical rotatory dispersion

PAGE

Polyacrylamide gel electrophoresis

RIA

Radioimmunoassay

ROESY

Rotating frame nuclear Overhauser enhanced spectroscopy

RP

Reversed phase

SPPS

Solid phase peptide synthesis

TLC

Thin layer chromatography

TOCSY

Total correlation spectroscopy

TOF

Time of flight

UV

Ultraviolet

Miscellaneous

Ab

Antibody

ACE

Angiotensin-converting enzyme

ACTH

Adrenocorticotropic hormone

Ag

Antigen

AIDS

Acquired immunodeficiency syndrome

ANP

Atrial natriuretic polypeptide

ATP

Adenosine triphosphate

BK

Bradykinin

BSA

Bovine serum albumin

CCK

Cholecystokinin

DNA

Deoxyribonucleic acid

FSH

Follicle stimulating hormone

GH

Growth hormone

HIV

Human immunodeficiency virus

LHRH

Luteinizing hormone releasing hormone

MAP

Multiple antigen peptide

NPY

Neuropeptide Y

OT

Oxytocin

PTH

Parathyroid hormone

QSAR

Quantitative structureactivity relationship

RNA

Ribonucleic acid

TASP

Template-assembled synthetic protein

TRH

Thyrotropin releasing hormone

VIP

Vasoactive intestinal peptide

VP

Vasopressin