Afatinib
- CAT# 200500
- CAS# 850140-72-6
- Purity >97%
WARNING: This product is for research use only, not for human or veterinary use.
Price and availability
Structure
Structure of Afatinib
CAS# 850140-72-6
Size Price Availability Quantity 100 mg $ 90 Same day
$90.00Add to cart
200 mg $ 150 Same day
$150.00Add to cart
500 mg $ 250 Same day
$250.00Add to cart
1000 mg $ 450 Same day
$450.00Add to cart
Pricing updated 2019-06-06 . Prices are subject to change without notice
Description:
Afatinib, also know as BIBW 2992, is an orally bioavailable dual receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity.
Technical data
IUPAC/Chemnical Name (S,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide. Synonym name BIBW-2992; BIBW 2992; BIBW2992. Afatinib free base; trade name: Gilotrif, Tomtovok and Tovok. CAS# 850140-72-6 (free base) Molecule Formla C24H25ClFN5O3 Molecule Weight 485.94 Appearance Powder Purity >97% Certificate of Analysis Lot#XPR61221 Lot#XPR70102 QC Data Lot#XPR61221 Lot#XPR70102 Safety Data Sheet (MSDS) Afatinib free base Shipping Condition Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. Storage Condition Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). Stability >2 years if stored properly Harmonized System (HS) Code 2934.99.3000 SMILES code O=C(NC1=CC2=C(NC3=CC=C(F)C(Cl)=C3)N=CN=C2C=C1O[C@@H]4COCC4)/C=C/CN(C)C InChi code InChI=1S/C24H25ClFN5O3/c1-31(2)8-3-4-23(32)30-21-11-17-20(12-22(21)34-16-7-9-33-13-16)27-14-28-24(17)29-15-5-6-19(26)18(25)10-15/h3-6,10-12,14,16H,7-9,13H2,1-2H3,(H,30,32)(H,27,28,29)/b4-3+/t16-/m0/s1 InChi key ULXXDDBFHOBEHA-CWDCEQMOSA-N
Structure
Structure of Afatinib
CAS# 850140-72-6
| Size | Price | Availability | Quantity | |
|---|---|---|---|---|
| 100 mg | $ 90 | Same day | $90.00Add to cart | |
| 200 mg | $ 150 | Same day | $150.00Add to cart | |
| 500 mg | $ 250 | Same day | $250.00Add to cart | |
| 1000 mg | $ 450 | Same day | $450.00Add to cart |
Description:
Afatinib, also know as BIBW 2992, is an orally bioavailable dual receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity.
Technical data
| IUPAC/Chemnical Name | (S,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide. |
| Synonym name | BIBW-2992; BIBW 2992; BIBW2992. Afatinib free base; trade name: Gilotrif, Tomtovok and Tovok. |
| CAS# | 850140-72-6 (free base) |
| Molecule Formla | C24H25ClFN5O3 |
| Molecule Weight | 485.94 |
| Appearance | Powder |
| Purity | >97% |
| Certificate of Analysis | Lot#XPR61221 Lot#XPR70102 |
| QC Data | Lot#XPR61221 Lot#XPR70102 |
| Safety Data Sheet (MSDS) | Afatinib free base |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Storage Condition | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Stability | >2 years if stored properly |
| Harmonized System (HS) Code | 2934.99.3000 |
| SMILES code | O=C(NC1=CC2=C(NC3=CC=C(F)C(Cl)=C3)N=CN=C2C=C1O[C@@H]4COCC4)/C=C/CN(C)C |
| InChi code | InChI=1S/C24H25ClFN5O3/c1-31(2)8-3-4-23(32)30-21-11-17-20(12-22(21)34-16-7-9-33-13-16)27-14-28-24(17)29-15-5-6-19(26)18(25)10-15/h3-6,10-12,14,16H,7-9,13H2,1-2H3,(H,30,32)(H,27,28,29)/b4-3+/t16-/m0/s1 |
| InChi key | ULXXDDBFHOBEHA-CWDCEQMOSA-N |