Afatinib

  • CAT# 200500
  • CAS# 850140-72-6
  • Purity >97%

Price and availability

Structure

Structure of Afatinib

CAS# 850140-72-6

Size Price Availability Quantity
100 mg$ 90

Same day

$90.00Add to cart

200 mg$ 150

Same day

$150.00Add to cart

500 mg$ 250

Same day

$250.00Add to cart

1000 mg$ 450

Same day

$450.00Add to cart

Pricing updated 2019-06-06 . Prices are subject to change without notice
Description:

Afatinib, also know as BIBW 2992, is an orally bioavailable dual receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity.

Technical data

IUPAC/Chemnical Name(S,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide.
Synonym nameBIBW-2992; BIBW 2992; BIBW2992. Afatinib free base; trade name: Gilotrif, Tomtovok and Tovok.
CAS#850140-72-6 (free base)
Molecule FormlaC24H25ClFN5O3
Molecule Weight485.94
AppearancePowder
Purity>97%
Certificate of AnalysisLot#XPR61221 Lot#XPR70102
QC DataLot#XPR61221 Lot#XPR70102
Safety Data Sheet (MSDS)Afatinib free base
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage ConditionDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Stability>2 years if stored properly
Harmonized System (HS) Code 2934.99.3000
SMILES code O=C(NC1=CC2=C(NC3=CC=C(F)C(Cl)=C3)N=CN=C2C=C1O[C@@H]4COCC4)/C=C/CN(C)C
InChi code InChI=1S/C24H25ClFN5O3/c1-31(2)8-3-4-23(32)30-21-11-17-20(12-22(21)34-16-7-9-33-13-16)27-14-28-24(17)29-15-5-6-19(26)18(25)10-15/h3-6,10-12,14,16H,7-9,13H2,1-2H3,(H,30,32)(H,27,28,29)/b4-3+/t16-/m0/s1
InChi keyULXXDDBFHOBEHA-CWDCEQMOSA-N