WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H556159
CAS#: 2446803-65-0
Description: CVN03650, also known as IL-17 modulator 4, is an IL-17 modulator. This compound was first reported in Journal of Medicinal Chemistry (2022), 65(13), 8828-8842 (Compound 23). This product has no formal name at the moment. For the convenience of communication, a temporal code name was therefore proposed according to Hodoodo Chemical Nomenclature (see web page: https://www.hodoodo.com/page/naming).
Hodoodo Cat#: H556159
Name: CVN03650
CAS#: 2446803-65-0
Chemical Formula: C27H34N6O2
Exact Mass: 474.27
Molecular Weight: 474.609
Elemental Analysis: C, 68.33; H, 7.22; N, 17.71; O, 6.74
Synonym: IL-17 modulator 4; CVN03650; CVN 03650; CVN 03650;
IUPAC/Chemical Name: 1H-Pyrazole-5-carboxamide, N-[(1S)-2,2-dicyclopropyl-1-[[[4-(3,5-dimethyl-1H-pyrazol-4-yl)phenyl]amino]carbonyl]ethyl]-1-(1-methylethyl)-
InChi Key: CQKVACARDGYEMU-VWLOTQADSA-N
InChi Code: InChI=1S/C27H34N6O2/c1-15(2)33-22(13-14-28-33)26(34)30-25(24(19-5-6-19)20-7-8-20)27(35)29-21-11-9-18(10-12-21)23-16(3)31-32-17(23)4/h9-15,19-20,24-25H,5-8H2,1-4H3,(H,29,35)(H,30,34)(H,31,32)/t25-/m0/s1
SMILES Code: O=C(C1=CC=NN1C(C)C)N[C@H](C(NC2=CC=C(C3=C(C)NN=C3C)C=C2)=O)C(C4CC4)C5CC5
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info: Journal of Medicinal Chemistry (2022), 65(13), 8828-8842
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 474.61 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
Journal of Medicinal Chemistry (2022), 65(13), 8828-8842