WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H122214
CAS#: 1381861-96-6
Description: C13-112-tri-tail is an ionizable lipid molecule containing a polar amino alcohol head group, three hydrophobic carbon-13 tails, and a PEG2 linker. The lipoid can be formulated into a lipid nanoparticle (LNP) to deliver anionic substrates in vitro and in vivo. This includes siRNA to induce gene silencing in a sequence-specific manner, CAS9 mRNA, and cytotoxic proteins.
Hodoodo Cat#: H122214
Name: C13-112-tri-tail
CAS#: 1381861-96-6
Chemical Formula: C45H94N2O5
Exact Mass: 742.72
Molecular Weight: 743.260
Elemental Analysis: C, 72.72; H, 12.75; N, 3.77; O, 10.76
Synonym: C13-112-tri-tail
IUPAC/Chemical Name: 14-(2-hydroxytridecyl)-17,20-dioxa-14,23-diazahexatriacontane-12,25-diol
InChi Key: SFPCEMORTGPRFG-UHFFFAOYSA-N
InChi Code: InChI=1S/C45H94N2O5/c1-4-7-10-13-16-19-22-25-28-31-43(48)40-46-34-36-51-38-39-52-37-35-47(41-44(49)32-29-26-23-20-17-14-11-8-5-2)42-45(50)33-30-27-24-21-18-15-12-9-6-3/h43-46,48-50H,4-42H2,1-3H3
SMILES Code: CCCCCCCCCCCC(O)CNCCOCCOCCN(CC(O)CCCCCCCCCCC)CC(CCCCCCCCCCC)O
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 743.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |