WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H525474
CAS#: 103294-47-9
Description: LY 150310 is a histamine H1-receptor antagonist. It can alter prostanoid concentrations in vitro and in vivo.
Hodoodo Cat#: H525474
Name: LY 150310
CAS#: 103294-47-9
Chemical Formula: C13H14N2
Exact Mass: 198.12
Molecular Weight: 198.260
Elemental Analysis: C, 78.75; H, 7.12; N, 14.13
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Synonym: LY 150310; LY-150310; LY150310.
IUPAC/Chemical Name: 1H-Imidazole, 1-(1,2,3,4-tetrahydro-1-naphthalenyl)-
InChi Key: RUKUDYPTXIUUKQ-UHFFFAOYSA-N
InChi Code: InChI=1S/C13H14N2/c1-2-6-12-11(4-1)5-3-7-13(12)15-9-8-14-10-15/h1-2,4,6,8-10,13H,3,5,7H2
SMILES Code: N1(C2CCCC3=C2C=CC=C3)C=CN=C1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 198.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Stengel PW, Dillard RD, Cho HL, Snyder DW, Spaethe SM, Pechous PA, Obenchain RL, Cockerham SL, Silbaugh SA. Bronchopulmonary actions of 1-(1,2,3,4-tetrahydro-1-naphthylenyl)-1H-imidazole, nitric acid salt (LY150310), a substituted imidazole, in the guinea pig. J Pharmacol Exp Ther. 1993 Nov;267(2):596-603. PubMed PMID: 8246133.
2: Merriman RL, Shackelford KA, Tanzer LR, Campbell JB, Bemis KG, Matsumoto K. Drug treatments for metastasis of the Lewis lung carcinoma: lack of correlation between inhibition of lung metastasis and survival. Cancer Res. 1989 Aug 15;49(16):4509-16. PubMed PMID: 2743339.