WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H130150
CAS#: N/A
Description: C4E8 is a selective α-glucosidase inhibitor.
Hodoodo Cat#: H130150
Name: C4E8
CAS#: N/A
Chemical Formula: C20H15N3O3
Exact Mass: 345.11
Molecular Weight: 345.358
Elemental Analysis: C, 69.56; H, 4.38; N, 12.17; O, 13.90
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Synonym: C4E8
IUPAC/Chemical Name: (E)-N'-((6-methyl-4-oxo-4H-chromen-3-yl)methylene)-1H-indole-2-carbohydrazide
InChi Key: PVTFVZQJZDTSMH-UFFVCSGVSA-N
InChi Code: InChI=1S/C20H15N3O3/c1-12-6-7-18-15(8-12)19(24)14(11-26-18)10-21-23-20(25)17-9-13-4-2-3-5-16(13)22-17/h2-11,22H,1H3,(H,23,25)/b21-10+
SMILES Code: O=C(C(N1)=CC2=C1C=CC=C2)N/N=C/C3=COC4=C(C=C(C)C=C4)C3=O
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 345.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1. Wu Y, Liu C, Hu L. Fragment-Based Dynamic Combinatorial Chemistry for Identification of Selective α-Glucosidase Inhibitors. ACS Med Chem Lett. 2022 Oct 19;13(11):1791-1796. doi: 10.1021/acsmedchemlett.2c00405. PMID: 36385930; PMCID: PMC9661702.