WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H326813
CAS#: 98185-20-7 (tartrate)
Description: Raclopride, also known as FLA 870, a selective antagonist on D2 dopamine receptor. Its selectivity to the cerebral D2 receptors is characterized by its respective Ki-values, which are as follows: 1.8, 3.5, 2400 and 18000 nM for D2, D3, D4 and D1 receptors respectively. It can be radiolabelled with radioisotopes, e.g. 3H or 11C and used as a tracer for in vitro imaging (autoradiography) as well as in vivo imaging positron emission tomography (PET). Images obtained by cerebral PET scanning (e.g. PET/CT or PET/MRI) allow the non-invasive assessment of the binding capacity of the cerebral D2 dopamine receptor, which can be useful for the diagnosis of movement disorders.
Hodoodo Cat#: H326813
Name: Raclopride tartrate
CAS#: 98185-20-7 (tartrate)
Chemical Formula: C19H26Cl2N2O9
Exact Mass: 496.10
Molecular Weight: 497.322
Elemental Analysis: C, 45.89; H, 5.27; Cl, 14.26; N, 5.63; O, 28.95
Related CAS #: 84225-95-6 (free base) 98185-20-7 (tartrate)
Synonym: FLA 870; FLA-870; FLA870; Raclopride tartrate
IUPAC/Chemical Name: (S)-3,5-dichloro-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-6-methoxybenzamide (2R,3R)-2,3-dihydroxysuccinate
InChi Key: QULBVRZTKPQGCR-NDAAPVSOSA-N
InChi Code: InChI=1S/C15H20Cl2N2O3.C4H6O6/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2;5-1(3(7)8)2(6)4(9)10/h7,9,20H,3-6,8H2,1-2H3,(H,18,21);1-2,5-6H,(H,7,8)(H,9,10)/t9-;1-,2-/m01/s1
SMILES Code: O=C(NC[C@H]1N(CC)CCC1)C2=C(OC)C(Cl)=CC(Cl)=C2O.O=C(O)[C@H](O)[C@@H](O)C(O)=O
Appearance: Solid powder
Purity: >97% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info: Reltated CAS# CAS#84225-95-6 (Raclopride free base) CAS#98185-20-7 (Raclopride tartrate)
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The following data is based on the product molecular weight 497.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
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