WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H556206
CAS#: 1515888-53-5
Description: UCB-9260 is an orally bioavailable TNF inhibitor. UCB-9260 inhibits TNF signalling by stabilising an asymmetric form of the trimer.
Hodoodo Cat#: H556206
Name: UCB-9260
CAS#: 1515888-53-5
Chemical Formula: C26H25N5O
Exact Mass: 423.21
Molecular Weight: 423.520
Elemental Analysis: C, 73.74; H, 5.95; N, 16.54; O, 3.78
Synonym: UCB-9260; UCB 9260; UCB9260;
IUPAC/Chemical Name: (1-(2,5-dimethylbenzyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-benzo[d]imidazol-2-yl)(pyridin-4-yl)methanol
InChi Key: RZGFWGNCSYUEPR-UHFFFAOYSA-N
InChi Code: InChI=1S/C26H25N5O/c1-17-4-5-18(2)21(12-17)16-31-24-13-20(22-14-28-30(3)15-22)6-7-23(24)29-26(31)25(32)19-8-10-27-11-9-19/h4-15,25,32H,16H2,1-3H3
SMILES Code: OC(C1=NC2=CC=C(C3=CN(C)N=C3)C=C2N1CC4=CC(C)=CC=C4C)C5=CC=NC=C5
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
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The following data is based on the product molecular weight 423.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
