WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H525932
CAS#: 1207481-21-7
Description: PF-46396 is a HIV maturation inhibitor. PF-46396 displayed potent activity against HIV-1 clade B. PF-46396 as a broadly active maturation inhibitor can be used against HIV-1 clade B and C and help in rational designing of novel analogs with reduced toxicity and increased efficacy for its potential use in clinics.
Hodoodo Cat#: H525932
Name: PF-46396
CAS#: 1207481-21-7
Chemical Formula: C27H29F3N2O
Exact Mass: 454.22
Molecular Weight: 454.537
Elemental Analysis: C, 71.35; H, 6.43; F, 12.54; N, 6.16; O, 3.52
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Synonym: PF-46396; PF 46396; PF46396.
IUPAC/Chemical Name: 1-[2-(4-tert-butylphenyl)-2-(2,3-dihydro-1H-inden-2-ylamino)ethyl]-3-(trifluoromethyl)pyridin-2-one
InChi Key: ARDZNPZYNMTXDH-UHFFFAOYSA-N
InChi Code: InChI=1S/C27H29F3N2O/c1-26(2,3)21-12-10-18(11-13-21)24(31-22-15-19-7-4-5-8-20(19)16-22)17-32-14-6-9-23(25(32)33)27(28,29)30/h4-14,22,24,31H,15-17H2,1-3H3
SMILES Code: O=C1C(C(F)(F)F)=CC=CN1CC(C2=CC=C(C(C)(C)C)C=C2)NC3CC4=C(C=CC=C4)C3
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
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The following data is based on the product molecular weight 454.54 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |