WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H471220
CAS#: 2108829-86-1 (HCl)
Description: KU-0058948 hydrochloride is a poly (ADP-ribose) polymerase (PARP) inhibitor that induces cell cycle arrest and apoptosis of primary myeloid leukemic cells and myeloid leukemic cell lines in vitro.
Hodoodo Cat#: H471220
Name: KU-0058948 hydrochloride
CAS#: 2108829-86-1 (HCl)
Chemical Formula: C21H22ClFN4O2
Exact Mass: 0.00
Molecular Weight: 416.880
Elemental Analysis: C, 60.50; H, 5.32; Cl, 8.50; F, 4.56; N, 13.44; O, 7.68
Related CAS #: 2108829-86-1 (HCl) 763111-49-5
Synonym: KU-0058948 hydrochloride; KU0058948 hydrochloride; KU 0058948 hydrochloride; KU-0058948 HCl
IUPAC/Chemical Name: 4-(3-(1,4-diazepane-1-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one hydrochloride
InChi Key: GXROJFUSWNEBPH-UHFFFAOYSA-N
InChi Code: InChI=1S/C21H21FN4O2.ClH/c22-18-7-6-14(12-17(18)21(28)26-10-3-8-23-9-11-26)13-19-15-4-1-2-5-16(15)20(27)25-24-19;/h1-2,4-7,12,23H,3,8-11,13H2,(H,25,27);1H
SMILES Code: O=C1NN=C(CC2=CC=C(F)C(C(N3CCNCCC3)=O)=C2)C4=C1C=CC=C4.[H]Cl
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
| Biological target: | |
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The following data is based on the product molecular weight 416.88 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
