IFM-2427

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H124878

CAS#: N/A

Description: IFM-2427 is a NLRP3 inhibitor.

Chemical Structure

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IFM-2427
CAS# N/A
Instruction

Theoretical Analysis

Hodoodo Cat#: H124878
Name: IFM-2427
CAS#: N/A
Chemical Formula: C19H24N4O3S2
Exact Mass: 420.13
Molecular Weight: 420.550
Elemental Analysis: C, 54.26; H, 5.75; N, 13.32; O, 11.41; S, 15.25

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: IFM-2427; IFM 2427; IFM2427

IUPAC/Chemical Name: (R)-N'-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)-2-(2-hydroxypropan-2-yl)thiazole-5-sulfonimidamide

InChi Key: LHVWNNYPUDZLSH-MUUNZHRXSA-N

InChi Code: InChI=1S/C19H24N4O3S2/c1-19(2,25)17-21-10-15(27-17)28(20,26)23-18(24)22-16-13-7-3-5-11(13)9-12-6-4-8-14(12)16/h9-10,25H,3-8H2,1-2H3,(H3,20,22,23,24,26)/t28-/m1/s1

SMILES Code: O=C(N=[S@@](C1=CN=C(C(C)(O)C)S1)(N)=O)NC2=C3CCCC3=CC4=C2CCC4

Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 420.55 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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Chen W, Xing J, Liu X, Wang S, Xing D. The role and transformative potential of IL-19 in atherosclerosis. Cytokine Growth Factor Rev. 2021 Dec;62:70-82. doi: 10.1016/j.cytogfr.2021.09.001. Epub 2021 Sep 21. PMID: 34600839.