Hexoprenaline Sulfate

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Hodoodo CAT#: H328804

CAS#: 32266-10-7 (sulfate)

Description: Hexoprenaline Sulfate, also known as Gynipral and ST-1512/SO4, is a selective beta2-adrenoreceptor agonist which is active in man as a bronchodilator by the oral or intravenous routes and by inhalation. Hexoprenaline Sulfate is indicated for use in the treatment of bronchospasm associated with obstructive airways diseases, including asthma, bronchitis and emphysema.


Chemical Structure

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Hexoprenaline Sulfate
CAS# 32266-10-7 (sulfate)

Theoretical Analysis

Hodoodo Cat#: H328804
Name: Hexoprenaline Sulfate
CAS#: 32266-10-7 (sulfate)
Chemical Formula: C22H34N2O10S
Exact Mass: 0.00
Molecular Weight: 518.578
Elemental Analysis: C, 50.96; H, 6.61; N, 5.40; O, 30.85; S, 6.18

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

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Related CAS #: 32266-10-7 (sulfate)   3215-70-1(free base)    

Synonym: Hexoprenaline Sulfate; Argocian; ST-1512; ST-1512; ST-1512; Gynipral

IUPAC/Chemical Name: 4,4'-((hexane-1,6-diylbis(azanediyl))bis(1-hydroxyethane-2,1-diyl))bis(benzene-1,2-diol) sulfate

InChi Key: CSCDCOQSIWXPSZ-UHFFFAOYSA-N

InChi Code: InChI=1S/C22H32N2O6.H2O4S/c25-17-7-5-15(11-19(17)27)13-21(29)23-9-3-1-2-4-10-24-22(30)14-16-6-8-18(26)20(28)12-16;1-5(2,3)4/h5-8,11-12,21-30H,1-4,9-10,13-14H2;(H2,1,2,3,4)

SMILES Code: OC(C1=CC=C(O)C(O)=C1)CNCCCCCCNCC(C2=CC=C(O)C(O)=C2)O.O=S(O)(O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info: Related CAS# 3215-70-1 (Hexoprenaline) 32266-10-7 (Hexoprenaline Sulfate)

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 518.58 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Trittenwein G, Rosegger H, Beitzke A, Lichtenegger W, Rosanelli K, Zeichen HL. [Heart function in infants and small children, whose mothers required tocolysis with hexoprenaline sulfate (Gynipral)]. Wien Klin Wochenschr. 1986 Sep 26;98(18):613-7. German. PubMed PMID: 3788179.

2: Rivier G, Nicole A, Stucki D, Regamey C. [Lesional pulmonary edema associated with tocolysis by hexoprenaline sulfate]. Schweiz Med Wochenschr. 1992 Feb 15;122(7):237-41. French. PubMed PMID: 1539126.

3: Niveiro E, Oehling A. [Hexoprenaline sulfate in the treatment of bronchospastic processes]. Allergol Immunopathol (Madr). 1974 Nov-Dec;2(6):387-98. Spanish. PubMed PMID: 4464780.

4: Mayer M, Minichmayr A, Klement F, Hroncek K, Wertaschnigg D, Arzt W, Wiesinger-Eidenberger G, Lechner E. Tocolysis with the β-2-sympathomimetic hexoprenaline increases occurrence of infantile haemangioma in preterm infants. Arch Dis Child Fetal Neonatal Ed. 2013 Mar;98(2):F108-11. doi: 10.1136/archdischild-2011-301030. Epub 2012 May 18. PubMed PMID: 22611112.

5: Hösli I, Sperschneider C, Drack G, Zimmermann R, Surbek D, Irion O; Swiss Society of Obstetrics and Gynecology. Tocolysis for preterm labor: expert opinion. Arch Gynecol Obstet. 2014 Apr;289(4):903-9. doi: 10.1007/s00404-013-3137-9. Epub 2014 Jan 3. Review. PubMed PMID: 24385286.

6: Anderson SD, Spiroglou M, Lindsay D. An evaluation of oral hexoprenaline sulphate (Ipradol) in exercise-induced asthma. Med J Aust. 1977 Dec 17;2(25):825-7. PubMed PMID: 349324.

7: Trofimov MV. [Peculiarities of treatment of ulcerative gastrointestinal hemorrhage in pregnant women]. Klin Khir. 2014 Jun;(6):8-10. Ukrainian. PubMed PMID: 25252542.

8: Neilson JP, West HM, Dowswell T. Betamimetics for inhibiting preterm labour. Cochrane Database Syst Rev. 2014 Feb 5;(2):CD004352. doi: 10.1002/14651858.CD004352.pub3. Review. PubMed PMID: 24500892.

9: Coleman AJ, Leary WP. Cardiovascular effects of hexoprenaline sulphate and salbutamol in man. S Afr Med J. 1973 Apr 14;47(14):621-4. PubMed PMID: 4144824.

10: Afschar P, Schöll W, Bader A, Bauer M, Winter R. A prospective randomised trial of atosiban versus hexoprenaline for acute tocolysis and intrauterine resuscitation. BJOG. 2004 Apr;111(4):316-8. PubMed PMID: 15008765.