Ro 31-0313

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H526185

CAS#: 77273-77-9

Description: Ro 31-0313 is a metabolite of Ro 03-8799, radiation sensitizing agent.


Chemical Structure

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Ro 31-0313
CAS# 77273-77-9

Theoretical Analysis

Hodoodo Cat#: H526185
Name: Ro 31-0313
CAS#: 77273-77-9
Chemical Formula: C11H18N4O4
Exact Mass: 270.13
Molecular Weight: 270.290
Elemental Analysis: C, 48.88; H, 6.71; N, 20.73; O, 23.68

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Ro 31-0313; Ro 310313; Ro-31-0313.

IUPAC/Chemical Name: 2-Nitro-alpha-piperidinomethyl-1-imidazole ethanol N-oxide

InChi Key: BZKCKUMYSBPPIC-UHFFFAOYSA-N

InChi Code: InChI=1S/C11H18N4O4/c1-11(16,9-12-5-3-2-4-6-12)13-7-8-14(17)10(13)15(18)19/h7-8,16H,2-6,9H2,1H3

SMILES Code: CC(N1C=C[N+]([O-])=C1[N+]([O-])=O)(CN2CCCCC2)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 270.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Walton MI, Bleehen NM, Workman P. Effects of localised tumour hyperthermia on pimonidazole (Ro 03-8799) pharmacokinetics in mice. Br J Cancer. 1989 May;59(5):667-73. PubMed PMID: 2736198; PubMed Central PMCID: PMC2247237.

2: Walton MI, Bleehen NM, Workman P. The effects of whole body hyperthermia on the pharmacokinetics and toxicity of the basic 2-nitroimidazole radiosensitizer Ro 03-8799 in mice. Br J Cancer. 1987 May;55(5):469-76. PubMed PMID: 3606940; PubMed Central PMCID: PMC2001726.

3: Malcolm SL, Lee A, Groves JK. High-performance liquid chromatographic analysis of the new hypoxic cell radiosensitiser, Ro 03-8799, in biological samples. J Chromatogr. 1983 Apr 8;273(2):327-33. PubMed PMID: 6863447.