WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H531308
CAS#: 186611-55-2
Description: SU 4313 is a bioactive chemical.
Hodoodo Cat#: H531308
Name: SU 4313
CAS#: 186611-55-2
Chemical Formula: C18H17NO
Exact Mass: 263.13
Molecular Weight: 263.340
Elemental Analysis: C, 82.10; H, 6.51; N, 5.32; O, 6.08
Synonym: SU 4313
IUPAC/Chemical Name: 1,3-Dihydro-3-[[4-(1-methylethyl)phenyl]methylene]-2H-indol-2-one
InChi Key: IRQQWCZKCUQNSO-WJDWOHSUSA-N
InChi Code: InChI=1S/C18H17NO/c1-12(2)14-9-7-13(8-10-14)11-16-15-5-3-4-6-17(15)19-18(16)20/h3-12H,1-2H3,(H,19,20)/b16-11-
SMILES Code: O=C1NC2=C(C=CC=C2)/C1=C/C3=CC=C(C(C)C)C=C3
Appearance: Yellow solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
| Biological target: | SU 4313 is a bioactive chemical. |
| In vitro activity: | To be determined |
| In vivo activity: | To be determined |
The following data is based on the product molecular weight 263.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | To be determined |
| In vitro protocol: | To be determined |
| In vivo protocol: | To be determined |
1: Weigl K, Jansen L, Chang-Claude J, Knebel P, Hoffmeister M, Brenner H. Family history and the risk of colorectal cancer: The importance of patients' history of colonoscopy. Int J Cancer. 2016 Nov 15;139(10):2213-20. doi: 10.1002/ijc.30284. PubMed PMID: 27459311.
2: Plumb AA, Pathiraja F, Nickerson C, Wooldrage K, Burling D, Taylor SA, Atkin WS, Halligan S. Appearances of screen-detected versus symptomatic colorectal cancers at CT colonography. Eur Radiol. 2016 Dec;26(12):4313-4322. Erratum in: Eur Radiol. 2016 Dec;26(12 ):4323-4324. PubMed PMID: 27048534; PubMed Central PMCID: PMC5101282.
3: Shen C, Wang D, Liu X, Gu B, Du Y, Wei FZ, Cao LL, Song B, Lu X, Yang Q, Zhu Q, Hou T, Li M, Wang L, Wang H, Zhao Y, Yang Y, Zhu WG. SET7/9 regulates cancer cell proliferation by influencing β-catenin stability. FASEB J. 2015 Oct;29(10):4313-23. doi: 10.1096/fj.15-273540. PubMed PMID: 26116705.
4: Mimae T, Suzuki K, Tsuboi M, Nagai K, Ikeda N, Mitsudomi T, Saji H, Okumura S, Okumura M, Yoshimura K, Okada M. Surgical Outcomes of Lung Cancer in Patients with Combined Pulmonary Fibrosis and Emphysema. Ann Surg Oncol. 2015 Dec;22 Suppl 3:S1371-9. doi: 10.1245/s10434-015-4577-1. PubMed PMID: 25956575.
5: Lansingh VC, Nano ME, Carter MJ, Zárate N, Resnikoff S, Eckert KA. Complexities and challenges of surgical data collection from cataract patients: comparison of cataract surgery rates between 2001 and 2008 in all provinces of Argentina. Arq Bras Oftalmol. 2014 Jan-Feb;77(1):25-9. PubMed PMID: 25076369.
6: Chen BD, Zhao WC, Dong JD, Sima H. Expression of GLP-1R protein and its clinical role in intrahepatic cholangiocarcinoma tissues. Mol Biol Rep. 2014 Jul;41(7):4313-20. doi: 10.1007/s11033-014-3302-7. PubMed PMID: 24577752.
7: Faught AM, Kry SF, Luo D, Molineu A, Bellezza D, Gerber RL, Davidson SE, Bosch W, Drzymala RE, Galvin J, Timmerman R, Sheehan J, Gillin MT, Ibbott GS, Followill DS. Development of a modified head and neck quality assurance phantom for use in stereotactic radiosurgery trials. J Appl Clin Med Phys. 2013 Jul 8;14(4):4313. doi: 10.1120/jacmp.v14i4.4313. PubMed PMID: 23835394.
8: Lee WH, Kim SW, Lim CH, Kim JS, Cho YK, Lee IS, Choi MG, Choi KY. Efficacy of endoscopic mucosal resection using a dual-channel endoscope compared with endoscopic submucosal dissection in the treatment of rectal neuroendocrine tumors. Surg Endosc. 2013 Nov;27(11):4313-8. doi: 10.1007/s00464-013-3050-0. PubMed PMID: 23807754.
9: Lessey BA, Higdon HL 3rd, Miller SE, Price TA. Intraoperative detection of subtle endometriosis: a novel paradigm for detection and treatment of pelvic pain associated with the loss of peritoneal integrity. J Vis Exp. 2012 Dec 21;(70). pii: 4313. doi: 10.3791/4313. PubMed PMID: 23288271; PubMed Central PMCID: PMC3576419.
10: Ito R, Katano I, Ida-Tanaka M, Kamisako T, Kawai K, Suemizu H, Aiso S, Ito M. Efficient xenoengraftment in severe immunodeficient NOD/Shi-scid IL2rγnull mice is attributed to a lack of CD11c+B220+CD122+ cells. J Immunol. 2012 Nov 1;189(9):4313-20. doi: 10.4049/jimmunol.1200820. PubMed PMID: 23018460.
11: Onyekwelu I, Khatib O, Zuckerman JD, Rokito AS, Kwon YW. The rising incidence of arthroscopic superior labrum anterior and posterior (SLAP) repairs. J Shoulder Elbow Surg. 2012 Jun;21(6):728-31. doi: 10.1016/j.jse.2012.02.001. PubMed PMID: 22608836.
12: Rusch VW, Hawes D, Decker PA, Martin SE, Abati A, Landreneau RJ, Patterson GA, Inculet RI, Jones DR, Malthaner RA, Cohen RG, Ballman K, Putnam JB Jr, Cote RJ. Occult metastases in lymph nodes predict survival in resectable non-small-cell lung cancer: report of the ACOSOG Z0040 trial. J Clin Oncol. 2011 Nov 10;29(32):4313-9. doi: 10.1200/JCO.2011.35.2500. PubMed PMID: 21990404; PubMed Central PMCID: PMC3221530.
13: Kakkos SK, Caprini JA, Geroulakos G, Nicolaides AN, Stansby GP, Tsolakis IA, Reddy DJ. Can combined (mechanical and pharmacological) modalities prevent fatal VTE? Int Angiol. 2011 Apr;30(2):115-22. Review. PubMed PMID: 21427647.
14: Karatepe O, Acet E, Battal M, Adas G, Kemik A, Altiok M, Kamali G, Koculu S, Catay A, Kamali S, Karahan S. Effects of glutamine and curcumin on bacterial translocation in jaundiced rats. World J Gastroenterol. 2010 Sep 14;16(34):4313-20. PubMed PMID: 20818815; PubMed Central PMCID: PMC2937112.
15: Terhune KP, Zaydfudim V, Abumrad NN. International medical graduates in general surgery: increasing needs, decreasing numbers. J Am Coll Surg. 2010 Jun;210(6):990-6. doi: 10.1016/j.jamcollsurg.2010.02.021. PubMed PMID: 20510809.
16: Gillmore JD, Lachmann HJ, Wechalekar A, Hawkins PN. Hereditary fibrinogen A alpha-chain amyloidosis: clinical phenotype and role of liver transplantation. Blood. 2010 May 27;115(21):4313; author reply 4314-5. doi: 10.1182/blood-2010-01-261750. PubMed PMID: 20508170.
17: Losiniecki A, Zuccarello M. Subarachnoid hemorrhage: effect on cerebral blood flow and cerebral metabolism. Front Biosci. 2008 Jan 1;13:1845-56. Review. PubMed PMID: 17981672.
18: Folman Y, Shabat S, Gepstein R. B-twin expandable spinal spacer for posterior lumbar interbody stabilization: mechanical testing. J Surg Orthop Adv. 2006 Winter;15(4):203-8. PubMed PMID: 17313932.
19: Sun HL, Gao S, Ma BQ, Su G. Long-range ferromagnetic ordering in two-dimensional coordination polymers Co[N(CN)2]2(L) [L = pyrazine dioxide (pzdo) and 2-methyl pyrazine dioxide (mpdo)] with dual mu- and mu3-[N(CN)2] bridges. Inorg Chem. 2003 Aug 25;42(17):5399-404. PubMed PMID: 12924913.
20: Brännström M, Wranning CA, Racho El-Akouri R. Transplantation of the uterus. Mol Cell Endocrinol. 2003 Apr 28;202(1-2):177-84. Review. PubMed PMID: 12770748.
