WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H530373
CAS#: 1796596-46-7 (sodium)
Description: NSC23005 is a p18INK inhibitor. NSC23005 potently promotes hematopoietic stem cell (HSC) expansion (ED50 = 5.21 nM).
Hodoodo Cat#: H530373
Name: NSC23005 sodium
CAS#: 1796596-46-7 (sodium)
Chemical Formula: C13H16NNaO4S
Exact Mass: 0.00
Molecular Weight: 305.324
Elemental Analysis: C, 51.14; H, 5.28; N, 4.59; Na, 7.53; O, 20.96; S, 10.50
Related CAS #: 1796596-46-7 (sodium) 6314-70-1 (free acid)
Synonym: p18SMI-40; NSC23005 sodium; NSC23005; NSC-23005; NSC 23005.
IUPAC/Chemical Name: Sodium 4-(N-cyclohexylsulfamoyl)benzoate
InChi Key: MLHFBDVMTRIQMW-UHFFFAOYSA-M
InChi Code: InChI=1S/C13H17NO4S.Na/c15-13(16)10-6-8-12(9-7-10)19(17,18)14-11-4-2-1-3-5-11;/h6-9,11,14H,1-5H2,(H,15,16);/q;+1/p-1
SMILES Code: O=C([O-])C1=CC=C(S(=O)(NC2CCCCC2)=O)C=C1.[Na+]
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info: Related CAS# CAS#1796596-46-7 (NSC23005 sodium) CAS#6314-70-1 (NSC23005)
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 305.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
Xie et al (2015) Discovery of novel INK4C small-molecule inhibitors to promote human and murine hematopoietic stem cell ex vivo expansion. Sci.Rep. 5 18115 PMID: 26681454