WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H531779
CAS#: 122089-44-5
Description: EP 171 is high agonist potency at TP-receptors.
Hodoodo Cat#: H531779
Name: EP 171
CAS#: 122089-44-5
Chemical Formula: C23H29FO5
Exact Mass: 404.20
Molecular Weight: 404.480
Elemental Analysis: C, 68.30; H, 7.23; F, 4.70; O, 19.78
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Synonym: EP 171; EP171; EP-171.
IUPAC/Chemical Name: (Z)-7-[(1S,4R,5R,6R)-5-[(E,3S)-4-(4-fluorophenoxy)-3-hydroxybut-1-enyl]-7-oxabicyclo[2.2.1]heptan-6-yl]hept-5-enoic acid
InChi Key: JEUSDRLWFSRHSX-XUEDOEMRSA-N
InChi Code: InChI=1S/C23H29FO5/c24-16-7-10-18(11-8-16)28-15-17(25)9-12-20-19(21-13-14-22(20)29-21)5-3-1-2-4-6-23(26)27/h1,3,7-12,17,19-22,25H,2,4-6,13-15H2,(H,26,27)/b3-1-,12-9+/t17-,19+,20+,21-,22+/m0/s1
SMILES Code: O=C(O)CCC/C=C\C[C@@H]1[C@@H](/C=C/[C@H](O)COC2=CC=C(F)C=C2)[C@@]3([H])CC[C@]1([H])O3
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 404.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Jones RL, Wilson NH, Lawrence RA. EP 171: a high affinity thromboxane A2-mimetic, the actions of which are slowly reversed by receptor blockade. Br J Pharmacol. 1989 Apr;96(4):875-87. PubMed PMID: 2743082; PubMed Central PMCID: PMC1854451.