L-750,667 TriHydrochloride
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Hodoodo CAT#: H532083

CAS#: 1021868-80-3

Description: L-750,667 TriHydrochloride is a selective D4 dopamine receptor antagonist.

Chemical Structure

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L-750,667 TriHydrochloride
CAS# 1021868-80-3
Instruction

Theoretical Analysis

Hodoodo Cat#: H532083
Name: L-750,667 TriHydrochloride
CAS#: 1021868-80-3
Chemical Formula: C18H22Cl3IN4
Exact Mass: 0.00
Molecular Weight: 527.657
Elemental Analysis: C, 40.97; H, 4.20; Cl, 20.16; I, 24.05; N, 10.62

Price and Availability

Size Price Availability Quantity
5mg USD 585 2 Weeks
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Synonym: L-750,667; L 750,667; L750,667.

IUPAC/Chemical Name: 3-[4-(4-Iodophenyl)piperazin-1-yl]methyl-1H-pyrrolo[2,3-b]pyridine trihydrochloride

InChi Key: YOURSPNOEWYAKO-UHFFFAOYSA-N

InChi Code: InChI=1S/C18H19IN4.3ClH/c19-15-3-5-16(6-4-15)23-10-8-22(9-11-23)13-14-12-21-18-17(14)2-1-7-20-18;;;/h1-7,12H,8-11,13H2,(H,20,21);3*1H

SMILES Code: IC1=CC=C(N2CCN(CC3=CNC4=NC=CC=C43)CC2)C=C1.[H]Cl.[H]Cl.[H]Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 527.66 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Kawano M, Takagi R, Kaneko A, Matsushita S. Berberine is a dopamine D1- and D2-like receptor antagonist and ameliorates experimentally induced colitis by suppressing innate and adaptive immune responses. J Neuroimmunol. 2015 Dec 15;289:43-55. doi: 10.1016/j.jneuroim.2015.10.001. PubMed PMID: 26616870.