PPD 10558

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H529010

CAS#: 805241-79-6

Description: PPD 10558, also known as RBx 10558, is a HMG-CoA reductase inhibitor potentially for treatment of primary hypercholesterolemia.


Chemical Structure

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PPD 10558
CAS# 805241-79-6

Theoretical Analysis

Hodoodo Cat#: H529010
Name: PPD 10558
CAS#: 805241-79-6
Chemical Formula: C34H37FN2O6
Exact Mass: 588.26
Molecular Weight: 588.676
Elemental Analysis: C, 69.37; H, 6.34; F, 3.23; N, 4.76; O, 16.31

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: PPD-10558; RBx-10558; PPD10558; RBx10558; PPD 10558; RBx 10558, bemfivastatin

IUPAC/Chemical Name: 7-(2-(4-fluorophenyl)-4-((4-(hydroxymethyl)phenyl)carbamoyl)-5-isopropyl-3-phenyl-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoic acid

InChi Key: PMFRPLBQEYHUMG-UHFFFAOYSA-N

InChi Code: InChI=1S/C34H37FN2O6/c1-21(2)32-31(34(43)36-26-14-8-22(20-38)9-15-26)30(23-6-4-3-5-7-23)33(24-10-12-25(35)13-11-24)37(32)17-16-27(39)18-28(40)19-29(41)42/h3-15,21,27-28,38-40H,16-20H2,1-2H3,(H,36,43)(H,41,42)

SMILES Code: O=C(O)CC(O)CC(O)CCN1C(C2=CC=C(F)C=C2)=C(C3=CC=CC=C3)C(C(NC4=CC=C(CO)C=C4)=O)=C1C(C)C

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 588.68 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Faqi AS, Prohaska D, Lopez R, McIntyre G. Developmental toxicity of the
HMG-CoA reductase inhibitor (PPD10558) in rats and rabbits. Birth Defects Res B
Dev Reprod Toxicol. 2012 Feb;95(1):23-37. doi: 10.1002/bdrb.20337. PubMed PMID:
22006546.