WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H532644
CAS#: 207572-69-8 (HCl)
Description: SB203186 is potent 5-HT4 receptor antagonist with high affinity for human atrial 5-HT4 receptors.
Hodoodo Cat#: H532644
Name: SB203186 HCl
CAS#: 207572-69-8 (HCl)
Chemical Formula: C16H21ClN2O2
Exact Mass: 0.00
Molecular Weight: 308.806
Elemental Analysis: C, 62.23; H, 6.85; Cl, 11.48; N, 9.07; O, 10.36
Related CAS #: 207572-69-8 (HCl) 398454-65-4 (free base)
Synonym: SB 203186 HCl; SB 203186 HCl; SB203186; SB-203186; SB203186 hydrochloride
IUPAC/Chemical Name: 1-Piperidinylethyl-1H-indole-3-carboxylate hydrochloride
InChi Key: QMMZZIUEHINBPH-UHFFFAOYSA-M
InChi Code: InChI=1S/C16H20N2O2.ClH/c19-16(20)14-12-18(15-7-3-2-6-13(14)15)11-10-17-8-4-1-5-9-17;/h2-3,6-7,12H,1,4-5,8-11H2,(H,19,20);1H/p-1
SMILES Code: O=C(O)C1=CN(C2=C1C=CC=C2)CCN3CCCCC3.[H]Cl
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
Solvent | Max Conc. mg/mL | Max Conc. mM | |
---|---|---|---|
Solubility | |||
Water | 10.0 | 32.46 |
The following data is based on the product molecular weight 308.81 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Parker SG, Taylor EM, Hamburger SA, Vimal M, Kaumann AJ. Blockade of human and porcine myocardial 5-HT4 receptors by SB 203186. Naunyn Schmiedebergs Arch Pharmacol. 1995 Dec;353(1):28-35. PubMed PMID: 8750913.