WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H532696
CAS#: 1197334-02-3 (SDZ 205557 Hydrochloride), 137196-67-9(SDZ 205557)
Description: SDZ 205557 Hydrochloride is a 5-HT3/5-HT4 receptor antagonist.
Hodoodo Cat#: H532696
Name: SDZ 205557 Hydrochloride
CAS#: 1197334-02-3 (SDZ 205557 Hydrochloride), 137196-67-9(SDZ 205557)
Chemical Formula: C14H22Cl2N2O3
Exact Mass: 336.10
Molecular Weight: 337.240
Elemental Analysis: C, 49.86; H, 6.58; Cl, 21.02; N, 8.31; O, 14.23
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Related CAS #: 1197334-02-3 (SDZ 205557 Hydrochloride);
Synonym: SDZ205557: SDZ-205557; SDZ 205557; SDZ 205557 HCl; SDZ 205557 Hydrochloride.
IUPAC/Chemical Name: 4-Amino-5-chloro-2-methoxybenzoic acid 2-(diethylamino)ethyl ester hydrochloride
InChi Key: JOWUQCJWCRNVMQ-UHFFFAOYSA-N
InChi Code: InChI=1S/C14H21ClN2O3.ClH/c1-4-17(5-2)6-7-20-14(18)10-8-11(15)12(16)9-13(10)19-3;/h8-9H,4-7,16H2,1-3H3;1H
SMILES Code: O=C(OCCN(CC)CC)C1=CC(Cl)=C(N)C=C1OC.[H]Cl
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 337.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Eglen RM, Alvarez R, Johnson LG, Leung E, Wong EH. The action of SDZ 205,557 at 5-hydroxytryptamine (5-HT3 and 5-HT4) receptors. Br J Pharmacol. 1993 Feb;108(2):376-82. PubMed PMID: 8448587; PubMed Central PMCID: PMC1907968.