WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H525936
CAS#: 1416872-50-8
Description: Sulfidefluor-7 AM is a novel hydrogen sulphide (H2S) fluorescent probe.
Hodoodo Cat#: H525936
Name: Sulfidefluor-7 AM
CAS#: 1416872-50-8
Chemical Formula: C31H23N7O12
Exact Mass: 685.14
Molecular Weight: 685.562
Elemental Analysis: C, 54.31; H, 3.38; N, 14.30; O, 28.00
Synonym: Sulfidefluor-7 AM
IUPAC/Chemical Name: N-[2-[(Acetyloxy)methoxy]-2-oxoethyl]-N-[(3',6'-diazido-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)carbonyl]glycine (acetyloxy)methyl ester
InChi Key: QIAZHSBWGCYJGQ-UHFFFAOYSA-N
InChi Code: InChI=1S/C31H23N7O12/c1-16(39)45-14-47-27(41)12-38(13-28(42)48-15-46-17(2)40)29(43)18-3-6-22-21(9-18)30(44)50-31(22)23-7-4-19(34-36-32)10-25(23)49-26-11-20(35-37-33)5-8-24(26)31/h3-11H,12-15H2,1-2H3
SMILES Code: O=C(OCOC(C)=O)CN(CC(OCOC(C)=O)=O)C(C1=CC2=C(C3(C4=C(OC5=C3C=CC(N=[N+]=[N-])=C5)C=C(N=[N+]=[N-])C=C4)OC2=O)C=C1)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 685.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Cheng Z, Garikipati VN, Nickoloff E, Wang C, Polhemus DJ, Zhou J, Benedict C, Khan M, Verma SK, Rabinowitz JE, Lefer D, Kishore R. Restoration of Hydrogen Sulfide Production in Diabetic Mice Improves Reparative Function of Bone Marrow Cells. Circulation. 2016 Nov 8;134(19):1467-1483. Epub 2016 Sep 22. PubMed PMID: 27660293; PubMed Central PMCID: PMC5101140.
2: Candela J, Velmurugan GV, White C. Hydrogen sulfide depletion contributes to microvascular remodeling in obesity. Am J Physiol Heart Circ Physiol. 2016 May 1;310(9):H1071-80. doi: 10.1152/ajpheart.00062.2016. Epub 2016 Mar 18. PubMed PMID: 26993223.