WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H561157
CAS#: 635-78-9
Description: Resorufin, also known as OUL47 or NSC12097, is an ARTD10 inhibitor. Resorufin is widely used as an indicator of cell viability in assays.
Hodoodo Cat#: H561157
Name: Resorufin
CAS#: 635-78-9
Chemical Formula: C12H7NO3
Exact Mass: 213.04
Molecular Weight: 213.190
Elemental Analysis: C, 67.61; H, 3.31; N, 6.57; O, 22.51
Synonym: Resorufin; OUL47; NSC12097; OUL-47; NSC-12097; OUL 47; NSC 12097
IUPAC/Chemical Name: 7-Hydroxy-3H-phenoxazin-3-one
InChi Key: HSSLDCABUXLXKM-UHFFFAOYSA-N
InChi Code: InChI=1S/C12H7NO3/c14-7-1-3-9-11(5-7)16-12-6-8(15)2-4-10(12)13-9/h1-6,14H
SMILES Code: O=C1C=CC2=NC3=C(C=C(O)C=C3)OC2=C1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 213.19 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Summers FA, Zhao B, Ganini D, Mason RP. Photooxidation of Amplex Red to resorufin: implications of exposing the Amplex Red assay to light. Methods Enzymol. 2013;526:1-17. doi: 10.1016/B978-0-12-405883-5.00001-6. Review. PubMed PMID: 23791091.
2: Jiao Y, Zhu B, Chen J, Duan X. Fluorescent sensing of fluoride in cellular system. Theranostics. 2015 Jan 1;5(2):173-87. doi: 10.7150/thno.9860. eCollection 2015. Review. PubMed PMID: 25553106; PubMed Central PMCID: PMC4279002.
3: Pomorski A, Krężel A. Exploration of biarsenical chemistry--challenges in protein research. Chembiochem. 2011 May 16;12(8):1152-67. doi: 10.1002/cbic.201100114. Epub 2011 Apr 28. Review. PubMed PMID: 21538762.
4: Löhr M, Hummel F, Faulmann G, Ringel J, Saller R, Hain J, Günzburg WH, Salmons B. Microencapsulated, CYP2B1-transfected cells activating ifosfamide at the site of the tumor: the magic bullets of the 21st century. Cancer Chemother Pharmacol. 2002 May;49 Suppl 1:S21-4. Epub 2002 Apr 12. Review. PubMed PMID: 12042985.
5: Deiss F, Sojic N, White DJ, Stoddart PR. Nanostructured optical fibre arrays for high-density biochemical sensing and remote imaging. Anal Bioanal Chem. 2010 Jan;396(1):53-71. doi: 10.1007/s00216-009-3211-0. Epub 2009 Nov 15. Review. PubMed PMID: 19916005.
6: Sarkar A, Ray D, Shrivastava AN, Sarker S. Molecular Biomarkers: their significance and application in marine pollution monitoring. Ecotoxicology. 2006 May;15(4):333-40. Epub 2006 May 5. Review. PubMed PMID: 16676218.