WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H571002
CAS#: 93132-85-5
Description: Arabinose 1,5-diphosphate, also known as A 1,5-BP, is a bisphosphatase inhibitor. Arabinose 1,5-diphosphate activated the kinase and inhibited the bisphosphatase.
Hodoodo Cat#: H571002
Name: Arabinose 1,5-diphosphate
CAS#: 93132-85-5
Chemical Formula: C5H12O11P2
Exact Mass: 309.99
Molecular Weight: 310.090
Elemental Analysis: C, 19.37; H, 3.90; O, 56.75; P, 19.98
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Synonym: Arabinose 1,5-diphosphate; A 1,5-BP. Arabinose 1,5-bisphosphate.
IUPAC/Chemical Name: ((2R,3S,4S,5S)-3,4-dihydroxy-5-(phosphonooxy)tetrahydrofuran-2-yl)methyl dihydrogen phosphate
InChi Key: AAAFZMYJJHWUPN-MBMOQRBOSA-N
InChi Code: InChI=1S/C5H12O11P2/c6-3-2(1-14-17(8,9)10)15-5(4(3)7)16-18(11,12)13/h2-7H,1H2,(H2,8,9,10)(H2,11,12,13)/t2-,3-,4+,5+/m1/s1
SMILES Code: OP(O[C@H](O1)[C@@H](O)[C@H](O)[C@H]1COP(O)(O)=O)(O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 310.09 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Pilkis SJ, McGrane MM, Kountz PD, el-Maghrabi MR, Pilkis J, Maryanoff BE, Reitz AB, Benkovic SJ. The effect of arabinose 1,5-bisphosphate on rat hepatic 6-phosphofructo-1-kinase and fructose-1,6-bisphosphatase. Biochem Biophys Res Commun. 1986 Jul 16;138(1):159-66. PubMed PMID: 3017313.