T-26c
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Hodoodo CAT#: H561310

CAS#: 869296-13-9 (free acid)

Description: T-26c is a highly potent, selective and cell-permeable matrix metalloproteinases 13 (MMP-13) inhibitor. T-26c also inhibits the breakdown of collagen in IL-1b and oncostatin M stimulated cartilage.


Chemical Structure

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T-26c
CAS# 869296-13-9 (free acid)

Theoretical Analysis

Hodoodo Cat#: H561310
Name: T-26c
CAS#: 869296-13-9 (free acid)
Chemical Formula: C24H21N3O6S
Exact Mass: 479.12
Molecular Weight: 479.510
Elemental Analysis: C, 60.12; H, 4.41; N, 8.76; O, 20.02; S, 6.69

Price and Availability

Size Price Availability Quantity
50mg USD 550
100mg USD 950
200mg USD 1650
500mg USD 2450
1g USD 3950
2g USD 6450
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Related CAS #: 69298-22-6 (sodium)   869296-13-9 (free acid),  

Synonym: T-26c, T26c, T 26c

IUPAC/Chemical Name: 4-(((2-((3-methoxybenzyl)carbamoyl)-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-5-yl)methoxy)methyl)benzoic acid

InChi Key: CDQRIIUMNLMHRH-UHFFFAOYSA-N

InChi Code: InChI=1S/C24H21N3O6S/c1-32-18-4-2-3-15(9-18)10-25-22(29)20-26-21(28)19-17(13-34-23(19)27-20)12-33-11-14-5-7-16(8-6-14)24(30)31/h2-9,13H,10-12H2,1H3,(H,25,29)(H,30,31)(H,26,27,28)

SMILES Code: O=C(O)C1=CC=C(COCC2=CSC(N=C(C(NCC3=CC=CC(OC)=C3)=O)N4)=C2C4=O)C=C1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 479.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Florent M, Noël T, Ruprich-Robert G, Da Silva B, Fitton-Ouhabi V, Chastin C, Papon N, Chapeland-Leclerc F. Nonsense and missense mutations in FCY2 and FCY1 genes are responsible for flucytosine resistance and flucytosine-fluconazole cross-resistance in clinical isolates of Candida lusitaniae. Antimicrob Agents Chemother. 2009 Jul;53(7):2982-90. doi: 10.1128/AAC.00880-08. Epub 2009 May 4. PubMed PMID: 19414575; PubMed Central PMCID: PMC2704628.