WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H571188
CAS#: 136451-98-4
Description: A 73209 is a nucleoside analog of the oxetanocin family. It originates from a class of compounds that inhibit viral DNA synthesis. A-73209 appears to be a potent and selective agent against varicella-zoster virus and herpes simplex virus infections.
Hodoodo Cat#: H571188
Name: A 73209
CAS#: 136451-98-4
Chemical Formula: C10H14N2O5
Exact Mass: 242.09
Molecular Weight: 242.230
Elemental Analysis: C, 49.58; H, 5.83; N, 11.56; O, 33.02
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Synonym: A 73209; A-73209; A73209
IUPAC/Chemical Name: 2,4(1H,3H)-Pyrimidinedione, 1-((2R,3R,4S)-3,4-bis(hydroxymethyl)-2-oxetanyl)-5-methyl-
InChi Key: NRDGYJVGNAAHDO-ZXFLCMHBSA-N
InChi Code: InChI=1S/C10H14N2O5/c1-5-2-12(10(16)11-8(5)15)9-6(3-13)7(4-14)17-9/h2,6-7,9,13-14H,3-4H2,1H3,(H,11,15,16)/t6-,7-,9-/m1/s1
SMILES Code: O=C1NC(C(C)=CN1[C@@H]2O[C@H](CO)[C@H]2CO)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 242.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Alder J, Mitten M, Norbeck D, Marsh K, Kern ER, Clement J. Efficacy of A-73209, a potent orally active agent against VZV and HSV infections. Antiviral Res. 1994 Feb;23(2):93-105. PubMed PMID: 8147583.