Septamycin

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H571248

CAS#: 54927-63-8

Description: Septamycin is a polycyclic, polyether, monocarboxylic acid antibiotic isolated from strain of Streptomyces albus. antibiotic.

Chemical Structure

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Septamycin
CAS# 54927-63-8
Instruction

Theoretical Analysis

Hodoodo Cat#: H571248
Name: Septamycin
CAS#: 54927-63-8
Chemical Formula: C48H82O16
Exact Mass: 914.56
Molecular Weight: 915.170
Elemental Analysis: C, 63.00; H, 9.03; O, 27.97

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Septamycin; A28695A; A 28695A; A-28695A

IUPAC/Chemical Name: (2R)-2-((2S,3R,4S,5S,6S)-2-hydroxy-6-(((2R,3R,4R,5S,7S,9R,10R)-2-((2S,2'R,5'R)-5'-((3S,5R,6S)-6-hydroxy-3,5,6-trimethyltetrahydro-2H-pyran-2-yl)octahydro-[2,2'-bifuran]-5-yl)-3,9-dimethoxy-2,4,10-trimethyl-1,6-dioxaspiro[4.5]decan-7-yl)methyl)-4-methoxy-5-(((2S,5S,6R)-5-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-3,5-dimethyltetrahydro-2H-pyran-2-yl)propanoic acid

InChi Key: QZVSDERYSHAHPU-LFEMCTADSA-N

InChi Code: InChI=1S/C48H82O16/c1-24-21-25(2)46(10,51)63-40(24)35-16-15-33(58-35)34-17-19-37(59-34)45(9)42(56-14)28(5)48(64-45)26(3)36(54-12)22-31(60-48)23-38-44(8,62-39-20-18-32(53-11)30(7)57-39)41(55-13)27(4)47(52,61-38)29(6)43(49)50/h24-42,51-52H,15-23H2,1-14H3,(H,49,50)/t24-,25+,26+,27+,28+,29-,30+,31-,32-,33+,34-,35+,36+,37?,38-,39-,40?,41-,42+,44-,45+,46-,47-,48-/m0/s1

SMILES Code: C[C@@H]1[C@@H](OC)[C@](C2O[C@H]([C@@H]3O[C@@H](C4[C@@H](C)C[C@@H](C)[C@@](C)(O)O4)CC3)CC2)(C)O[C@]1([C@H](C)[C@H](OC)C5)O[C@@H]5C[C@H]6[C@@](O[C@H]7CC[C@H](OC)[C@@H](C)O7)(C)[C@@H](OC)[C@@H](C)[C@]([C@@H](C)C(O)=O)(O)O6

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 915.17 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Rodios NA, Anteunis MJ. Solution conformation of septamycin and its sodium salt. J Antibiot (Tokyo). 1978 Apr;31(4):294-301. PubMed PMID: 659327.

2: Keller-Juslén C, King HD, Kis ZL, von Wartburg A. Septamycin, a polyether antibiotic. Taxonomy, fermentation, isolation and characterization. J Antibiot (Tokyo). 1975 Nov;28(11):854-9. PubMed PMID: 172482.

3: Meingassner JG, Hildebrandt J, Leskova R, Mieth H. Laboratory studies on the anticoccidial activity of septamycin. Poult Sci. 1977 Jul;56(4):1281-8. PubMed PMID: 605085.

4: Ricketts AP, Dirlam JP, Shively JE. Anticoccidial efficacy and chicken toleration of potent new polyether ionophores. 1. The septamycin relative CP-82,009. Poult Sci. 1992 Oct;71(10):1626-30. PubMed PMID: 1454680.

5: Siegel MM, McGahren WJ, Tomer KB, Chang TT. Applications of fast atom bombardment mass spectrometry and fast atom bombardment mass spectrometry-mass spectrometry to the maduramicins and other polyether antibiotics. Biomed Environ Mass Spectrom. 1987 Jan;14(1):29-38. PubMed PMID: 2952192.

6: Dirlam JP, Belton AM, Bordner J, Cullen WP, Huang LH, Kojima Y, Maeda H, Nishiyama S, Oscarson JR, Ricketts AP, et al. CP-82,009, a potent polyether anticoccidial related to septamycin and produced by Actinomadura sp. J Antibiot (Tokyo). 1992 Mar;45(3):331-40. PubMed PMID: 1577662.