WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H571331
CAS#: 125378-99-6
Description: Azidobenzamidotaurocholate is a bile acid transporting protein.
Hodoodo Cat#: H571331
Name: Azidobenzamidotaurocholate
CAS#: 125378-99-6
Chemical Formula: C33H49N5O7S
Exact Mass: 659.34
Molecular Weight: 659.840
Elemental Analysis: C, 60.07; H, 7.49; N, 10.61; O, 16.97; S, 4.86
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Synonym:
IUPAC/Chemical Name: Ethanesulfonic acid, 2-(((3alpha,5beta,7alpha,12alpha)-7-((4-azidobenzoyl)amino)-3,12-dihydroxy-24-oxocholan-24-yl)amino)-
InChi Key: AKTCPEQKKNHWEG-YHVVQYQXSA-N
InChi Code: InChI=1S/C33H49N5O7S/c1-19(4-11-29(41)35-14-15-46(43,44)45)24-9-10-25-30-26(18-28(40)33(24,25)3)32(2)13-12-23(39)16-21(32)17-27(30)36-31(42)20-5-7-22(8-6-20)37-38-34/h5-8,19,21,23-28,30,39-40H,4,9-18H2,1-3H3,(H,35,41)(H,36,42)(H,43,44,45)/t19-,21+,23-,24-,25+,26+,27-,28+,30+,32+,33-/m1/s1
SMILES Code: C[C@H](CCC(NCCS(=O)(O)=O)=O)[C@H]1CC[C@@]2([H])[C@]3([H])[C@H](NC(C4=CC=C(N=[N+]=[N-])C=C4)=O)C[C@]5([H])C[C@H](O)CC[C@]5(C)[C@@]3([H])C[C@H](O)[C@]12C
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
| Biological target: | |
| In vitro activity: | |
| In vivo activity: |
The following data is based on the product molecular weight 659.84 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
1: Ziegler K, Elsner RH. Functional molecular mass of the 14C azidobenzamidotaurocholic acid binding proteins in hepatocellular bile acid transport systems. Biochim Biophys Acta. 1992 Jan 31;1103(2):229-32. PubMed PMID: 1543707.
2: Ziegler K, Frimmer M, Müllner S, Fasold H. Bile acid binding proteins in
hepatocellular membranes of newborn and adult rats. Identification of transport proteins with azidobenzamidotauro[14C]cholate ([14C]ABATC). Biochim Biophys Acta. 1989 Apr 14;980(2):161-8. PubMed PMID: 2930783.
3: Ziegler K, Frimmer M, Kessler H, Haupt A. Azidobenzamido-008, a new photosensitive substrate for the 'multispecific bile acid transporter' of hepatocytes: evidence for a common transport system for bile acids and cyclosomatostatins in basolateral membranes. Biochim Biophys Acta. 1988 Nov 22;945(2):263-72. PubMed PMID: 2903768.
4: Wenzel U, Ziegler K. Binding proteins for cyclosomatostatins and bile acids in basolateral plasma membranes of rat liver. Biochim Biophys Acta. 1994 Jul 13;1193(1):17-23. PubMed PMID: 8038188.
