SB-226552

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H561516

CAS#: 883724-08-1

Description: SB-226552 is an aryloxypropanolamine selective beta3AR agonist. Beta3- is a putative atypical beta-adrenoceptors in humans.

Chemical Structure

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SB-226552
CAS# 883724-08-1
Instruction

Theoretical Analysis

Hodoodo Cat#: H561516
Name: SB-226552
CAS#: 883724-08-1
Chemical Formula: C24H34NO6P
Exact Mass: 463.21
Molecular Weight: 463.510
Elemental Analysis: C, 62.19; H, 7.39; N, 3.02; O, 20.71; P, 6.68

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: SB-226552; SB 226552; SB226552;

IUPAC/Chemical Name: cyclohexyl((4-(2-(((R)-2-hydroxy-3-(4-hydroxyphenoxy)propyl)amino)ethyl)phenoxy)methyl)phosphinic acid

InChi Key: DZFSTAUMUPHORN-OAQYLSRUSA-N

InChi Code: InChI=1S/C24H34NO6P/c26-20-8-12-22(13-9-20)30-17-21(27)16-25-15-14-19-6-10-23(11-7-19)31-18-32(28,29)24-4-2-1-3-5-24/h6-13,21,24-27H,1-5,14-18H2,(H,28,29)/t21-/m1/s1

SMILES Code: O=P(C1CCCCC1)(COC2=CC=C(CCNC[C@@H](O)COC3=CC=C(O)C=C3)C=C2)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 463.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Sennitt MV, Kaumann AJ, Molenaar P, Beeley LJ, Young PW, Kelly J, Chapman H, Henson SM, Berge JM, Dean DK, Kotecha NR, Morgan HK, Rami HK, Ward RW, Thompson M, Wilson S, Smith SA, Cawthorne MA, Stock MJ, Arch JR. The contribution of classical (beta1/2-) and atypical beta-adrenoceptors to the stimulation of human white adipocyte lipolysis and right atrial appendage contraction by novel beta3-adrenoceptor agonists of differing selectivities. J Pharmacol Exp Ther. 1998 Jun;285(3):1084-95. Erratum in: J Pharmacol Exp Ther 1998 Dec;287(3):1135. PubMed PMID: 9618411.