WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H571364
CAS#: 1432043-31-6 (HCl)
Description: WAY267464 is a nonpeptide small-molecule OT agonists that may be used for modulation of potency, selectivity over the structurally similar vasopressin receptors, CNS penetration, and oral bioavailability. WAY267464 produces anxiolytic effects.
Hodoodo Cat#: H571364
Name: WAY267464 HCl
CAS#: 1432043-31-6 (HCl)
Chemical Formula: C32H37Cl2N7O4
Exact Mass: 581.28
Molecular Weight: 654.593
Elemental Analysis: C, 58.72; H, 5.70; Cl, 10.83; N, 14.98; O, 9.78
Related CAS #: 847375-16-0 (free base) 1432043-31-6 (HCl)
Synonym: WAY267464; WAY 267464; WAY-267464; WAY 267,464 dihydrochloride, WAY 267464 dihydrochloride, WAY-267,464 dihydrochloride, WAY267464 dihydrochloride
IUPAC/Chemical Name: 4-(3,5-dihydroxybenzyl)-N-(2-methyl-4-(1-methyl-1,4,5,10-tetrahydrobenzo[b]pyrazolo[3,4-e][1,4]diazepine-5-carbonyl)benzyl)piperazine-1-carboxamide dihydrochloride
InChi Key: OTFWXMFLPMUDFP-UHFFFAOYSA-N
InChi Code: InChI=1S/C32H35N7O4.2ClH/c1-21-13-23(31(42)39-20-25-18-34-36(2)30(25)35-28-5-3-4-6-29(28)39)7-8-24(21)17-33-32(43)38-11-9-37(10-12-38)19-22-14-26(40)16-27(41)15-22;;/h3-8,13-16,18,35,40-41H,9-12,17,19-20H2,1-2H3,(H,33,43);2*1H
SMILES Code: O=C(N1CCN(CC2=CC(O)=CC(O)=C2)CC1)NCC3=CC=C(C(N4C5=CC=CC=C5NC(N(C)N=C6)=C6C4)=O)C=C3C.[H]Cl.[H]Cl
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
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The following data is based on the product molecular weight 654.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
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In vivo protocol: |
1: Lacivita E, Perrone R, Margari L, Leopoldo M. Targets for Drug Therapy for Autism Spectrum Disorder: Challenges and Future Directions. J Med Chem. 2017 Oct 30. doi: 10.1021/acs.jmedchem.7b00965. [Epub ahead of print] PubMed PMID: 29039668.