WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H584103
CAS#: 24028-59-9
Description: B1912 is an antibacterial agent.
Hodoodo Cat#: H584103
Name: B1912
CAS#: 24028-59-9
Chemical Formula: C30H29ClN4
Exact Mass: 480.21
Molecular Weight: 481.040
Elemental Analysis: C, 74.91; H, 6.08; Cl, 7.37; N, 11.65
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: B1912; B-1912; B 1912.
IUPAC/Chemical Name: 8-Chloro-3-(cyclohexylmino)-3,5-dihydro-N,5-diphenyl-2-phenazinamine
InChi Key: HTAJQJZZHQMHBK-UHFFFAOYSA-N
InChi Code: InChI=1S/C30H29ClN4/c31-21-16-17-29-27(18-21)34-28-19-25(32-22-10-4-1-5-11-22)26(33-23-12-6-2-7-13-23)20-30(28)35(29)24-14-8-3-9-15-24/h1,3-5,8-11,14-20,23,26,32-33H,2,6-7,12-13H2
SMILES Code: ClC1=CC2=C(C=C1)N(C3=CC=CC=C3)C4=CC(NC5CCCCC5)C(NC6=CC=CC=C6)=CC4=N2
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
| Biological target: | |
| In vitro activity: | |
| In vivo activity: |
The following data is based on the product molecular weight 481.04 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
1: Moynihan R. Canadian media company demands right to publish direct to consumer drug advertising. BMJ. 2009 May 8;338:b1912. doi: 10.1136/bmj.b1912. PubMed PMID: 19429658.
2: Morrison NE. Abortifacient activity of B1912. Int J Lepr Other Mycobact Dis. 1979 Dec;47(4):613-4. PubMed PMID: 122637.
3: Reich CV, de la Cruz E. The effect on pregnant mice of 0.05% B1912 fed in the diet. Int J Lepr Other Mycobact Dis. 1979 Dec;47(4):612-3. PubMed PMID: 122636.
4: Morrison NE, Marley GM. Comparative DNA binding studies with clofazimine and B1912. Int J Lepr Other Mycobact Dis. 1977 Apr-Jun;45(2):188-9. PubMed PMID: 561764.
5: Holmes IB, Banerjee DK, Hilson GR. Effect of rifampin, clofazimine, and B1912 on the viability of Mycobacterium leprae in established mouse footpad infection. Proc Soc Exp Biol Med. 1976 Apr;151(4):637-41. PubMed PMID: 772686.
6: Banerjee DK, Holmes IB. In vitro and in vivo studies of the action of rifampicin, clofazimine and B1912 on Mycobacterium marinum. Chemotherapy. 1976;22(3-4):242-52. PubMed PMID: 1269290.
