WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H526552
CAS#: 2376-65-0
Description: Fluphenazine Decanoate Dihydrochloride is an antipsychotic agent, blocking postsynaptic dopamine D2 receptors in the limbic, cortical system and basal ganglia.
Hodoodo Cat#: H526552
Name: Fluphenazine Decanoate Dihydrochloride
CAS#: 2376-65-0
Chemical Formula: C32H46Cl2F3N3O2S
Exact Mass: 663.26
Molecular Weight: 664.690
Elemental Analysis: C, 57.82; H, 6.98; Cl, 10.67; F, 8.57; N, 6.32; O, 4.81; S, 4.82
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: Fluphenazine Decanoate Dihydrochloride
IUPAC/Chemical Name: 2-[4-[3-[2-(Trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethyl decanoate dihydrochloride
InChi Key: IJIYWOFSPALWMA-UHFFFAOYSA-N
InChi Code: InChI=1S/C32H44F3N3O2S.2ClH/c1-2-3-4-5-6-7-8-14-31(39)40-24-23-37-21-19-36(20-22-37)17-11-18-38-27-12-9-10-13-29(27)41-30-16-15-26(25-28(30)38)32(33,34)35;;/h9-10,12-13,15-16,25H,2-8,11,14,17-24H2,1H3;2*1H
SMILES Code: CCCCCCCCCC(OCCN1CCN(CCCN2C3=C(C=CC=C3)SC4=CC=C(C(F)(F)F)C=C24)CC1)=O.[H]Cl.[H]Cl
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 664.69 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Midha KK, Marder SR, Jaworski TJ, McKay G, Hubbard JW, Hawes EM, Van Putten T, Wirshing WC, Aravagiri M. Clinical perspectives of some neuroleptics through development and application of their assays. Ther Drug Monit. 1993 Jun;15(3):179-89. Review. PubMed PMID: 8101398.
2: Dudley J, Rauw G, Hawes EM, Keegan DL, Midha KK. Correlation of fluphenazine plasma levels versus clinical response in patients: a pilot study. Prog Neuropsychopharmacol Biol Psychiatry. 1983;7(4-6):791-5. PubMed PMID: 6686710.
3: Hinterhuber H, Platz T, Schwarz S. [The plasma prolactin level under fluphenazine treatment (author's transl)]. Wien Med Wochenschr. 1980 Sep 15;130(17):566-70. German. PubMed PMID: 7456470.
4: Whelpton R, Curry SH. Methods for study of fluphenazine kinetics in man. J Pharm Pharmacol. 1976 Dec;28(12):869-73. PubMed PMID: 12260.