WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H561672
CAS#: 1323359-80-3
Description: ST362 is an anticancer agent. It acts by disrupting DNA repair and halting growth in prostate, colon, lung and breast cancer cells.
Hodoodo Cat#: H561672
Name: ST362
CAS#: 1323359-80-3
Chemical Formula: C25H21NO6S
Exact Mass: 463.11
Molecular Weight: 463.500
Elemental Analysis: C, 64.78; H, 4.57; N, 3.02; O, 20.71; S, 6.92
This product is not in stock, which may be available by custom synthesis.
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Synonym: ST362; ST-362; ST 362;
IUPAC/Chemical Name: (2E)-2-[[(2,5-Dihydro-4-methyl-5-oxo-2-furanyl)oxy]methylene]-7-(2,3-dihydrothieno[3,4-b]-1,4-dioxin-5-yl)-1,4-dihydro-1,4-dimethyl-cyclopent[b]indol-3(2H)-one
InChi Key: GJUAGRMNTHWYBB-MHWRWJLKSA-N
InChi Code: InChI=1S/C25H21NO6S/c1-12-8-19(32-25(12)28)31-10-16-13(2)20-15-9-14(4-5-17(15)26(3)21(20)22(16)27)24-23-18(11-33-24)29-6-7-30-23/h4-5,8-11,13,19H,6-7H2,1-3H3/b16-10+
SMILES Code: O=C(C(N1C)=C2C3=C1C=CC(C4=C5C(OCCO5)=CS4)=C3)/C(C2C)=C/OC(C=C6C)OC6=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 463.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Freitag C, Michael GB, Kadlec K, Hassel M, Schwarz S. Detection of plasmid-borne extended-spectrum β-lactamase (ESBL) genes in Escherichia coli isolates from bovine mastitis. Vet Microbiol. 2017 Feb;200:151-156. doi: 10.1016/j.vetmic.2016.08.010. Epub 2016 Aug 16. PubMed PMID: 27566885.
2: Vanegas JM, Cienfuegos AV, Ocampo AM, López L, del Corral H, Roncancio G, Sierra P, Echeverri-Toro L, Ospina S, Maldonado N, Robledo C, Restrepo A, Jiménez JN. Similar frequencies of Pseudomonas aeruginosa isolates producing KPC and VIM carbapenemases in diverse genetic clones at tertiary-care hospitals in Medellín, Colombia. J Clin Microbiol. 2014 Nov;52(11):3978-86. doi: 10.1128/JCM.01879-14. Epub 2014 Sep 10. PubMed PMID: 25210071; PubMed Central PMCID: PMC4313234.
3: Sun H, Wang H, Xu Y, Jones RN, Costello AJ, Liu Y, Li G, Chen M, Mendes RE. Molecular characterization of vancomycin-resistant Enterococcus spp. clinical isolates recovered from hospitalized patients among several medical institutions in China. Diagn Microbiol Infect Dis. 2012 Dec;74(4):399-403. doi: 10.1016/j.diagmicrobio.2012.09.006. Epub 2012 Oct 23. PubMed PMID: 23099304.
4: Podkowik M, Bystroń J, Bania J. Genotypes, antibiotic resistance, and virulence factors of staphylococci from ready-to-eat food. Foodborne Pathog Dis. 2012 Jan;9(1):91-3. doi: 10.1089/fpd.2011.0962. Epub 2011 Oct 11. PubMed PMID: 21988402.
5: Cortés P, Blanc V, Mora A, Dahbi G, Blanco JE, Blanco M, López C, Andreu A, Navarro F, Alonso MP, Bou G, Blanco J, Llagostera M. Isolation and characterization of potentially pathogenic antimicrobial-resistant Escherichia coli strains from chicken and pig farms in Spain. Appl Environ Microbiol. 2010 May;76(9):2799-805. doi: 10.1128/AEM.02421-09. Epub 2010 Mar 12. PubMed PMID: 20228098; PubMed Central PMCID: PMC2863447.
6: Zhu X, Zheng B, Wang S, Willems RJ, Xue F, Cao X, Li Y, Bo S, Liu J. Molecular characterisation of outbreak-related strains of vancomycin-resistant Enterococcus faecium from an intensive care unit in Beijing, China. J Hosp Infect. 2009 Jun;72(2):147-54. doi: 10.1016/j.jhin.2009.02.014. Epub 2009 Mar 31. PubMed PMID: 19339079.