WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H526633
CAS#: 68401-81-0 (free acid)
Description: Ceftizoxime, also known as FK 749, is a broad-spectrum, beta-lactamase-resistant, third-generation cephalosporin, binding to and inactivating penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall.
Hodoodo Cat#: H526633
Name: Ceftizoxime
CAS#: 68401-81-0 (free acid)
Chemical Formula: C13H13N5O5S2
Exact Mass: 383.04
Molecular Weight: 383.397
Elemental Analysis: C, 40.73; H, 3.42; N, 18.27; O, 20.86; S, 16.72
Related CAS #: 68401-82-1 (sodium) 68401-81-0 (free acid)
Synonym: Ceftizoxime; FK-749; FK 749; FK749; FR 13749; FR-13749; FR13749; Cefizox;
IUPAC/Chemical Name: (6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
InChi Key: NNULBSISHYWZJU-LLKWHZGFSA-N
InChi Code: InChI=1S/C13H13N5O5S2/c1-23-17-7(5-4-25-13(14)15-5)9(19)16-8-10(20)18-6(12(21)22)2-3-24-11(8)18/h2,4,8,11H,3H2,1H3,(H2,14,15)(H,16,19)(H,21,22)/b17-7-/t8-,11-/m1/s1
SMILES Code: O=C(C(N12)=CCS[C@]2([H])[C@H](NC(/C(C3=CSC(N)=N3)=N\OC)=O)C1=O)O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 383.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
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