WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H571422
CAS#: 2463-84-5
Description: Dicapthon is an insecticide that is toxic to humans. It increases occurrence of abnormal cell frequency, decreases the mitotic index, and decreases nuclear division index.
Hodoodo Cat#: H571422
Name: Dicapthon
CAS#: 2463-84-5
Chemical Formula: C8H9ClNO5PS
Exact Mass: 296.96
Molecular Weight: 297.650
Elemental Analysis: C, 32.28; H, 3.05; Cl, 11.91; N, 4.71; O, 26.88; P, 10.41; S, 10.77
This product is not in stock, which may be available by custom synthesis.
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Synonym: Dicapthon; Captex; AC4124; AC-4124; AC 4124; ENT 17035; ENT-17035; ENT17035
IUPAC/Chemical Name: Phosphorothioic acid, O-(2-chloro-4-nitrophenyl) O,O-dimethyl ester
InChi Key: OTKXWJHPGBRXCR-UHFFFAOYSA-N
InChi Code: InChI=1S/C8H9ClNO5PS/c1-13-16(17,14-2)15-8-4-3-6(10(11)12)5-7(8)9/h3-5H,1-2H3
SMILES Code: S=P(OC)(OC)OC1=CC=C([N+]([O-])=O)C=C1Cl
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
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The following data is based on the product molecular weight 297.65 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
1: Liman R. Mutagenicity and genotoxicity of dicapthon insecticide. Cytotechnology. 2014 Oct;66(5):741-51. doi: 10.1007/s10616-013-9623-x. Epub 2014 Jan 31. PubMed PMID: 24477548; PubMed Central PMCID: PMC4158013.
2: Baughman RG, Hall GB. Two organophosphorus pesticides: methyl parathion and dicapthon. Acta Crystallogr C Struct Chem. 2014 Oct;70(Pt 10):975-7. doi: 10.1107/S2053229614020233. Epub 2014 Sep 28. PubMed PMID: 25279599.
3: Bowman BT, Sans WW. Further water solubility determinations of insecticidal compounds. J Environ Sci Health B. 1983;18(2):221-7. PubMed PMID: 6853964.
4: Hoehamer CF, Mazur CS, Wolfe NL. Purification and partial characterization of an acid phosphatase from Spirodela oligorrhiza and its affinity for selected organophosphate pesticides. J Agric Food Chem. 2005 Jan 12;53(1):90-7. PubMed PMID: 15631514.
5: Pant CP, Joshi GP, Rosen P, Pearson JA, Renaud P, Ramasamy M, Vandekar M. A village-scale trial of OMS-214 (Dicapthon) for the control of Anopheles gambiae and Anopheles funestus in northern Nigeria. Bull World Health Organ. 1969;41(2):311-5. PubMed PMID: 5308704; PubMed Central PMCID: PMC2427419.
