WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H561737
CAS#: 15763-12-9
Description: N6-Allyladenosine is an RNA labeling probe that acts through both metabolic and enzyme-assisted manners.
Hodoodo Cat#: H561737
Name: N6-Allyladenosine
CAS#: 15763-12-9
Chemical Formula: C13H17N5O4
Exact Mass: 307.13
Molecular Weight: 307.310
Elemental Analysis: C, 50.81; H, 5.58; N, 22.79; O, 20.82
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Synonym: N6-Allyladenosine; N6 Allyladenosine; a6A; N-Allyladenosine; N Allyladenosine;
IUPAC/Chemical Name: (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-[6-(prop-2-enylamino)purin-9-yl]oxolane-3,4-diol
InChi Key: WTYYPLSFICPDGL-QYVSTXNMSA-N
InChi Code: InChI=1S/C13H17N5O4/c1-2-3-14-11-8-12(16-5-15-11)18(6-17-8)13-10(21)9(20)7(4-19)22-13/h2,5-7,9-10,13,19-21H,1,3-4H2,(H,14,15,16)/t7-,9-,10-,13-/m1/s1
SMILES Code: O[C@@H]1[C@@H](CO)O[C@@H](N2C=NC3=C(NCC=C)N=CN=C23)[C@@H]1O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
| Biological target: | |
| In vitro activity: | |
| In vivo activity: |
The following data is based on the product molecular weight 307.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
1: Shu X, Dai Q, Wu T, Bothwell IR, Yue Y, Zhang Z, Cao J, Fei Q, Luo M, He C, Liu J. N(6)-Allyladenosine: A New Small Molecule for RNA Labeling Identified by Mutation Assay. J Am Chem Soc. 2017 Dec 6;139(48):17213-17216. doi: 10.1021/jacs.7b06837. Epub 2017 Nov 15. PubMed PMID: 29116772.
2: Dassano A, Mancuso M, Giardullo P, De Cecco L, Ciuffreda P, Santaniello E, Saran A, Dragani TA, Colombo F. N(6)-isopentenyladenosine and analogs activate the NRF2-mediated antioxidant response. Redox Biol. 2014 Mar 6;2:580-9. doi: 10.1016/j.redox.2014.03.001. eCollection 2014. PubMed PMID: 24688894; PubMed Central PMCID: PMC3969604.
3: Spector T, Beacham LM 3rd. Guanosine monophosphate synthetase from Escherichia coli B-96. Inhibition by nucleosides. J Biol Chem. 1975 Apr 25;250(8):3101-7. PubMed PMID: 164459.
