WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H527751
CAS#: 77408-67-4
Description: P18IN011 is a novel p18(INK4C) inhibitor.
Hodoodo Cat#: H527751
Name: P18IN011
CAS#: 77408-67-4
Chemical Formula: C15H12N2O5S
Exact Mass: 332.05
Molecular Weight: 332.330
Elemental Analysis: C, 54.21; H, 3.64; N, 8.43; O, 24.07; S, 9.65
Synonym: P18IN 011; P18IN-011; P18IN011
IUPAC/Chemical Name: 1,2-Benzoxazol-3-yl 4-acetamidobenzenesulfonate
InChi Key: SIXNKGXJEIVCDH-UHFFFAOYSA-N
InChi Code: InChI=1S/C15H12N2O5S/c1-10(18)16-11-6-8-12(9-7-11)23(19,20)22-15-13-4-2-3-5-14(13)21-17-15/h2-9H,1H3,(H,16,18)
SMILES Code: O=S(C1=CC=C(NC(C)=O)C=C1)(OC2=NOC3=CC=CC=C23)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 332.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Lefkowitz RJ. Identification of adenylate cyclase-coupled beta-adrenergic receptors with radiolabeled beta-adrenergic antagonists. Biochem Pharmacol. 1975 Sep 15;24(18):1651-8. PubMed PMID: 11.