WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H584310
CAS#: 84392-17-6
Description: Xenalipin is a hypolipidemic that reduces blood cholesterol and triglycerides in rats.
Hodoodo Cat#: H584310
Name: Xenalipin
CAS#: 84392-17-6
Chemical Formula: C14H9F3O2
Exact Mass: 266.06
Molecular Weight: 266.219
Elemental Analysis: C, 63.16; H, 3.41; F, 21.41; O, 12.02
Synonym: Xenalipin; BW 207U
IUPAC/Chemical Name: (1,1'-Biphenyl)-2-carboxylic acid, 4'-(trifluoromethyl)-
InChi Key: IQOMYCGTGFGDFN-UHFFFAOYSA-N
InChi Code: InChI=1S/C14H9F3O2/c15-14(16,17)10-7-5-9(6-8-10)11-3-1-2-4-12(11)13(18)19/h1-8H,(H,18,19)
SMILES Code: O=C(C1=CC=CC=C1C2=CC=C(C(F)(F)F)C=C2)O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 266.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Lewis MC, Hodgson GL, Shumaker TK, Namm DH. Evaluation of the hypolipidemic activity of xenalipin in experimental animals. Atherosclerosis. 1987 Mar;64(1):27-35. PubMed PMID: 3689493.
2: Liu KM, Zhang R, Duan XF. Room-temperature cobalt-catalyzed arylation of aromatic acids: overriding the ortho-selectivity via the oxidative assembly of carboxylate and aryl titanate reagents using oxygen. Org Biomol Chem. 2016 Feb 7;14(5):1593-8. doi: 10.1039/c5ob02496j. PubMed PMID: 26732625.