WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H341022
CAS#: 55528-52-4
Description: Antibiotic Z-1159-1 is a biochemical.
Hodoodo Cat#: H341022
Name: Antibiotic Z-1159-1
CAS#: 55528-52-4
Chemical Formula: C21H40N4O13
Exact Mass: 556.26
Molecular Weight: 556.566
Elemental Analysis: C, 45.32; H, 7.24; N, 10.07; O, 37.37
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: Antibiotic Z-1159-1; Z-1159-1.
IUPAC/Chemical Name: D-Streptamine, O-2-amino-2-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(beta-D-xylofuranosyl-(1-5))-N(sup 1)-(4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-
InChi Key: NRBAPKVHONIXPV-UHFFFAOYSA-N
InChi Code: InChI=1S/C21H40N4O13/c22-2-1-8(28)19(34)25-7-3-6(23)17(37-20-11(24)15(32)13(30)9(4-26)35-20)18(12(7)29)38-21-16(33)14(31)10(5-27)36-21/h6-18,20-21,26-33H,1-5,22-24H2,(H,25,34)
SMILES Code: C1C(C(C(C(C1NC(=O)C(CCN)O)O)OC2C(C(C(O2)CO)O)O)OC3C(C(C(C(O3)CO)O)O)N)N
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 556.57 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
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11: Sikri K, Duggal P, Kumar C, Batra SD, Vashist A, Bhaskar A, Tripathi K, Sethi T, Singh A, Tyagi JS. Multifaceted remodeling by vitamin C boosts sensitivity of Mycobacterium tuberculosis subpopulations to combination treatment by anti-tubercular drugs. Redox Biol. 2018 Jan 3;15:452-466. doi: 10.1016/j.redox.2017.12.020. [Epub ahead of print] PubMed PMID: 29413958.
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14: Zheng T, Li Sip YY, Leong MB, Huo Q. Linear self-assembly formation between gold nanoparticles and aminoglycoside antibiotics. Colloids Surf B Biointerfaces. 2018 Jan 29;164:185-191. doi: 10.1016/j.colsurfb.2018.01.027. [Epub ahead of print] PubMed PMID: 29413595.
15: Omwenga EO, Hensel A, Shitandi A, Goycoolea FM. Chitosan nanoencapsulation of flavonoids enhances their quorum sensing and biofilm formation inhibitory activities against an E.coli Top 10 biosensor. Colloids Surf B Biointerfaces. 2018 Jan 31;164:125-133. doi: 10.1016/j.colsurfb.2018.01.019. [Epub ahead of print] PubMed PMID: 29413589.
16: Woehlk C, von Bülow A, Kriegbaum M, Backer V, Porsbjerg C. Allergic asthma is associated with increased risk of infections requiring antibiotics. Ann Allergy Asthma Immunol. 2018 Feb;120(2):169-176.e1. doi: 10.1016/j.anai.2017.11.015. PubMed PMID: 29413341.
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