UBP618

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H555173

CAS#: 1333110-86-3

Description: UBP618 is a pan-inhibitor of GluN1/GluN2 receptors.

Chemical Structure

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UBP618
CAS# 1333110-86-3
Instruction

Theoretical Analysis

Hodoodo Cat#: H555173
Name: UBP618
CAS#: 1333110-86-3
Chemical Formula: C17H11BrO3
Exact Mass: 341.99
Molecular Weight: 343.176
Elemental Analysis: C, 59.50; H, 3.23; Br, 23.28; O, 13.99

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: UBP618; UBP-618; UBP 618.

IUPAC/Chemical Name: 4-Bromo-3-hydroxy-7-phenyl-naphthalene-2-carboxylic acid

InChi Key: UISPFOJJZIPYLC-UHFFFAOYSA-N

InChi Code: InChI=1S/C17H11BrO3/c18-15-13-7-6-11(10-4-2-1-3-5-10)8-12(13)9-14(16(15)19)17(20)21/h1-9,19H,(H,20,21)

SMILES Code: O=C(C1=C(O)C(Br)=C2C=CC(C3=CC=CC=C3)=CC2=C1)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 343.18 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Monaghan DT, Irvine MW, Costa BM, Fang G, Jane DE. Pharmacological modulation
of NMDA receptor activity and the advent of negative and positive allosteric
modulators. Neurochem Int. 2012 Sep;61(4):581-92. doi:
10.1016/j.neuint.2012.01.004. Epub 2012 Jan 17. Review. PubMed PMID: 22269804;
PubMed Central PMCID: PMC3360989.


2: Costa BM, Irvine MW, Fang G, Eaves RJ, Mayo-Martin MB, Laube B, Jane DE,
Monaghan DT. Structure-activity relationships for allosteric NMDA receptor
inhibitors based on 2-naphthoic acid. Neuropharmacology. 2012 Mar;62(4):1730-6.
doi: 10.1016/j.neuropharm.2011.11.019. Epub 2011 Dec 6. PubMed PMID: 22155206;
PubMed Central PMCID: PMC3269548.