UBP714
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    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H555176

CAS#: 773109-55-0

Description: UBP714 is a derivative of the NMDA receptor negative allosteric modulator UBP608 (SML0606). UBP714 also enhanced NMDAR mediated field EPSPs in the CA1 region of the hippocampus. UBP714 is therefore a novel template for the development of potent and subunit selective NMDAR potentiators that may have therapeutic applicability in the treatment of patients with cognitive deficits or schizophrenia.

Chemical Structure

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UBP714
CAS# 773109-55-0
Instruction

Theoretical Analysis

Hodoodo Cat#: H555176
Name: UBP714
CAS#: 773109-55-0
Chemical Formula: C11H7BrO4
Exact Mass: 281.95
Molecular Weight: 283.077
Elemental Analysis: C, 46.67; H, 2.49; Br, 28.23; O, 22.61

Price and Availability

Size Price Availability Quantity
5mg USD 255
25mg USD 650
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Synonym: UBP714; UBP-714; UBP 714.

IUPAC/Chemical Name: 6-Bromo-4-methyl-2-oxo-2H-1-benzopyran-3-carboxylic acid

InChi Key: BWBWVUJRXNIUMA-UHFFFAOYSA-N

InChi Code: InChI=1S/C11H7BrO4/c1-5-7-4-6(12)2-3-8(7)16-11(15)9(5)10(13)14/h2-4H,1H3,(H,13,14)

SMILES Code: O=C(C1=C(C)C2=CC(Br)=CC=C2OC1=O)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 283.08 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Irvine MW, Costa BM, Volianskis A, Fang G, Ceolin L, Collingridge GL, Monaghan
DT, Jane DE. Coumarin-3-carboxylic acid derivatives as potentiators and
inhibitors of recombinant and native N-methyl-D-aspartate receptors. Neurochem
Int. 2012 Sep;61(4):593-600. doi: 10.1016/j.neuint.2011.12.020. Epub 2012 Jan 13.
PubMed PMID: 22265875; PubMed Central PMCID: PMC3394894.