WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H555186
CAS#: 2102196-57-4
Description: MDK6574, also known as FAA1 agonist-1, is a FAA1 agonist. MDK6574 has CAS#2102196-57-4. The last 4 digit of its CAS# is used for naming for the convenience of scientific communication.
Hodoodo Cat#: H555186
Name: MDK6574
CAS#: 2102196-57-4
Chemical Formula: C21H17ClO5S
Exact Mass: 416.05
Molecular Weight: 416.872
Elemental Analysis: C, 60.51; H, 4.11; Cl, 8.50; O, 19.19; S, 7.69
Synonym: FAA1 agonist-1; FAA1 agonist 1; FAA1 agonist1; MDK6574; MDK-6574; MDK 6574.
IUPAC/Chemical Name: 2-((4-((2'-chloro-[1,1'-biphenyl]-3-yl)methoxy)phenyl)sulfonyl)acetic acid
InChi Key: YEFZZALZTNOYEA-UHFFFAOYSA-N
InChi Code: InChI=1S/C21H17ClO5S/c22-20-7-2-1-6-19(20)16-5-3-4-15(12-16)13-27-17-8-10-18(11-9-17)28(25,26)14-21(23)24/h1-12H,13-14H2,(H,23,24)
SMILES Code: ClC1=CC=CC=C1C2=CC(COC3=CC=C(S(CC(O)=O)(=O)=O)C=C3)=CC=C2
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
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The following data is based on the product molecular weight 416.87 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | |
| In vitro protocol: | |
| In vivo protocol: |
1. Li Z, et al. Discovery of phenylsulfonyl acetic acid derivatives with improved efficacy and safety as potent free fatty acid receptor 1 agonists for the treatment of type 2 diabetes. Eur J Med Chem. 2017 Sep 29;138:458-479.
