WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H581118
CAS#: 143490-50-0
Description: Nematocyphol is triterpene constituents from Euphorbia nematocypha Hand-Mazz. Seven triterpenoids have been isolated from the roots of Euphorbia nematocypha Hand-Mazz. through chromatography on 20% AgNO3-silica gel. One of them was identified as a new compound named nematocyphol on the basis of spectral data (IR, EIMS, 1H-NMR and 13C-NMR). Its structure was deduced as IVa. Other compounds were identified as nepehinol acetate (I), germanicol acetate (II), euphol (III), tanaxastanol (Va), 24-methylenecycloartanol (VIa) and nepehinol (VIIa). These compounds were obtained for the first time from this plant.
Hodoodo Cat#: H581118
Name: Nematocyphol
CAS#: 143490-50-0
Chemical Formula: C30H50O
Exact Mass: 426.39
Molecular Weight: 426.730
Elemental Analysis: C, 84.44; H, 11.81; O, 3.75
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: Nematocyphol;
IUPAC/Chemical Name: (1R,3aR,5aS,7aR,9S,11aR,11bR,13aS,13bR)-1-isopropyl-3a,5a,8,8,11a,13a-hexamethyl-2,3,3a,4,5,5a,7,7a,8,9,10,11,11a,11b,12,13,13a,13b-octadecahydro-1H-cyclopenta[a]chrysen-9-ol
InChi Key: QOYZWNYLMKAORW-AFYZKSQYSA-N
InChi Code: InChI=1S/C30H50O/c1-19(2)20-11-14-27(5)17-18-29(7)22-9-10-23-26(3,4)24(31)13-15-28(23,6)21(22)12-16-30(29,8)25(20)27/h9,19-21,23-25,31H,10-18H2,1-8H3/t20-,21+,23+,24+,25-,27-,28-,29-,30+/m1/s1
SMILES Code: CC(C)[C@H]1CC[C@]2([C@H]1[C@@]3(CC[C@H]4C(=CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)O)C)[C@]3(CC2)C)C)C
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 426.73 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Cao D, Su YL, Yang JS. [Triterpene constituents from Euphorbia nematocypha
Hand-Mazz]. Yao Xue Xue Bao. 1992;27(6):445-51. Chinese. PubMed PMID: 1442072.