Mulberroside C

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H562263

CAS#: 102841-43-0

Description: Mulberroside C is an inhibitor of HCV replicon cell growth isolated from root barks of Morus atropurpurea.


Chemical Structure

img
Mulberroside C
CAS# 102841-43-0

Theoretical Analysis

Hodoodo Cat#: H562263
Name: Mulberroside C
CAS#: 102841-43-0
Chemical Formula: C24H26O9
Exact Mass: 458.16
Molecular Weight: 458.460
Elemental Analysis: C, 62.88; H, 5.72; O, 31.41

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @hodoodo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Mulberroside C; Mulberroside-C;

IUPAC/Chemical Name: (2S,3R,4S,5R)-2-[3-Hydroxy-5-(6-hydroxy-7,7-dimethyl-5,6-dihydrofuro[3,2-g]chromen-2-yl)phenoxy]oxane-3,4,5-triol

InChi Key: OHVJCFZJKPEJRL-BOWLQXBNSA-N

InChi Code: InChI=1S/C24H26O9/c1-24(2)20(27)7-12-3-11-6-17(32-18(11)9-19(12)33-24)13-4-14(25)8-15(5-13)31-23-22(29)21(28)16(26)10-30-23/h3-6,8-9,16,20-23,25-29H,7,10H2,1-2H3/t16-,20?,21+,22-,23+/m1/s1

SMILES Code: O[C@H]1[C@H](OC2=CC(C(O3)=CC4=C3C=C5C(CC(O)C(C)(C)O5)=C4)=CC(O)=C2)OC[C@@H](O)[C@@H]1O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 458.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: He XR, Han SY, Li XH, Zheng WX, Pang LN, Jiang ST, Li PP. Chinese medicine Bu-Fei decoction attenuates epithelial-mesenchymal transition of non-small cell lung cancer via inhibition of transforming growth factor β1 signaling pathway in vitro and in vivo. J Ethnopharmacol. 2017 May 23;204:45-57. doi: 10.1016/j.jep.2017.04.008. Epub 2017 Apr 12. PubMed PMID: 28412214.

2: Chaita E, Lambrinidis G, Cheimonidi C, Agalou A, Beis D, Trougakos I, Mikros E, Skaltsounis AL, Aligiannis N. Anti-Melanogenic Properties of Greek Plants. A Novel Depigmenting Agent from Morus alba Wood. Molecules. 2017 Mar 23;22(4). pii: E514. doi: 10.3390/molecules22040514. PubMed PMID: 28333105.

3: Ko JA, Park JY, Kwon HJ, Ryu YB, Jeong HJ, Park SJ, Kim CY, Oh HM, Park CS, Lim YH, Kim D, Rho MC, Lee WS, Kim YM. Purification and functional characterization of the first stilbene glucoside-specific β-glucosidase isolated from Lactobacillus kimchi. Enzyme Microb Technol. 2014 Dec;67:59-66. doi: 10.1016/j.enzmictec.2014.09.001. Epub 2014 Sep 16. PubMed PMID: 25442950.

4: Wang CP, Zhang LZ, Li GC, Shi YW, Li JL, Zhang XC, Wang ZW, Ding F, Liang XM. Mulberroside A protects against ischemic impairment in primary culture of rat cortical neurons after oxygen-glucose deprivation followed by reperfusion. J Neurosci Res. 2014 Jul;92(7):944-54. doi: 10.1002/jnr.23374. Epub 2014 Mar 31. PubMed PMID: 24687774.

5: Li Y, Huang L, Zeng X, Zhong G, Ying M, Huang M, Bi H. Down-regulation of P-gp expression and function after Mulberroside A treatment: potential role of protein kinase C and NF-kappa B. Chem Biol Interact. 2014 Apr 25;213:44-50. doi: 10.1016/j.cbi.2014.02.004. Epub 2014 Feb 14. PubMed PMID: 24530447.

6: Jo SP, Kim JK, Lim YH. Antihyperlipidemic effects of stilbenoids isolated from Morus alba in rats fed a high-cholesterol diet. Food Chem Toxicol. 2014 Mar;65:213-8. doi: 10.1016/j.fct.2013.12.040. Epub 2014 Jan 7. PubMed PMID: 24407019.

7: Yang ZG, Matsuzaki K, Takamatsu S, Kitanaka S. Inhibitory effects of constituents from Morus alba var. multicaulis on differentiation of 3T3-L1 cells and nitric oxide production in RAW264.7 cells. Molecules. 2011 Jul 19;16(7):6010-22. doi: 10.3390/molecules16076010. PubMed PMID: 21772233.

8: Liu YH, Mo SL, Bi HC, Hu BF, Li CG, Wang YT, Huang L, Huang M, Duan W, Liu JP, Wei MQ, Zhou SF. Regulation of human pregnane X receptor and its target gene cytochrome P450 3A4 by Chinese herbal compounds and a molecular docking study. Xenobiotica. 2011 Apr;41(4):259-80. doi: 10.3109/00498254.2010.537395. Epub 2010 Nov 30. PubMed PMID: 21117944.

9: Wu D, Zhang X, Huang X, He X, Wang G, Ye W. [Chemical constituents from root barks of Morus atropurpurea]. Zhongguo Zhong Yao Za Zhi. 2010 Aug;35(15):1978-82. Chinese. PubMed PMID: 20931850.

10: Tan YX, Liu C, Chen RY. [2-Arylbenzofuran derivatives from Morus wittiorum]. Yao Xue Xue Bao. 2008 Nov;43(11):1119-22. Chinese. PubMed PMID: 19239031.

11: Lee HY, Yum JH, Rho YK, Oh SJ, Choi HS, Chang HB, Choi DH, Leem MJ, Choi EJ, Ryu JM, Hwang SB. Inhibition of HCV replicon cell growth by 2-arylbenzofuran derivatives isolated from Mori Cortex Radicis. Planta Med. 2007 Nov;73(14):1481-5. Epub 2007 Oct 18. PubMed PMID: 17948170.

12: Li H, Cheng KW, Cho CH, He Z, Wang M. Oxyresveratrol as an antibrowning agent for cloudy apple juices and fresh-cut apples. J Agric Food Chem. 2007 Apr 4;55(7):2604-10. Epub 2007 Mar 3. PubMed PMID: 17335224.

13: El-Beshbishy HA, Singab AN, Sinkkonen J, Pihlaja K. Hypolipidemic and antioxidant effects of Morus alba L. (Egyptian mulberry) root bark fractions supplementation in cholesterol-fed rats. Life Sci. 2006 May 1;78(23):2724-33. Epub 2005 Nov 28. PubMed PMID: 16313926.

14: Du J, He ZD, Jiang RW, Ye WC, Xu HX, But PP. Antiviral flavonoids from the root bark of Morus alba L. Phytochemistry. 2003 Apr;62(8):1235-8. PubMed PMID: 12648543.

15: Syah YM, Achmad SA, Ghisalberti EL, Hakim EH, Iman MZ, Makmur L, Mujahiddin D. Andalasin A, a new stilbene dimer from Morus macroura. Fitoterapia. 2000 Dec;71(6):630-5. PubMed PMID: 11077168.

16: Kimura Y, Okuda H, Nomura T, Fukai T, Arichi S. Effects of phenolic constituents from the mulberry tree on arachidonate metabolism in rat platelets. J Nat Prod. 1986 Jul-Aug;49(4):639-44. PubMed PMID: 3097265.