Ractopamine HCl
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    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H562319

CAS#: 90274-24-1

Description: Ractopamine HCl is a beta-Adrenergic agonist. It acts by being a full agonist at the TAAR1.

Chemical Structure

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Ractopamine HCl
CAS# 90274-24-1
Instruction

Theoretical Analysis

Hodoodo Cat#: H562319
Name: Ractopamine HCl
CAS#: 90274-24-1
Chemical Formula: C18H24ClNO3
Exact Mass: 0.00
Molecular Weight: 337.840
Elemental Analysis: C, 63.99; H, 7.16; Cl, 10.49; N, 4.15; O, 14.21

Price and Availability

Size Price Availability Quantity
250mg USD 285 2 Weeks
1g USD 585 2 Weeks
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Synonym: Ractopamine HCl; Ractopamine Hydrochloride;

IUPAC/Chemical Name: 4-(1-hydroxy-2-((4-(4-hydroxyphenyl)butan-2-yl)amino)ethyl)phenol hydrochloride

InChi Key: JHGSLSLUFMZUMK-UHFFFAOYSA-N

InChi Code: InChI=1S/C18H23NO3.ClH/c1-13(2-3-14-4-8-16(20)9-5-14)19-12-18(22)15-6-10-17(21)11-7-15;/h4-11,13,18-22H,2-3,12H2,1H3;1H

SMILES Code: OC1=CC=C(C=C1)C(CNC(CCC2=CC=C(C=C2)O)C)O.Cl

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 337.84 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Mendoza SM, Boyd RD, Zier-Rush CE, Ferket PR, Haydon KD, van Heugten E. Effect of natural betaine and ractopamine HCl on whole-body and carcass growth in pigs housed under high ambient temperatures. J Anim Sci. 2017 Jul;95(7):3047-3056. doi: 10.2527/jas.2017.1622. PubMed PMID: 28727090.

2: Cadaret CN, Beede KA, Riley HE, Yates DT. Acute exposure of primary rat soleus muscle to zilpaterol HCl (β2 adrenergic agonist), TNFα, or IL-6 in culture increases glucose oxidation rates independent of the impact on insulin signaling or glucose uptake. Cytokine. 2017 Aug;96:107-113. doi: 10.1016/j.cyto.2017.03.014. Epub 2017 Apr 5. PubMed PMID: 28390265; PubMed Central PMCID: PMC5483180.

3: Ebarb SM, Phelps KJ, Drouillard JS, Maddock-Carlin KR, Vaughn MA, Burnett DD, Noel JA, Van Bibber-Krueger CL, Paulk CB, Grieger DM, Gonzalez JM. Effects of anabolic implants and ractopamine-HCl on muscle fiber morphometrics, collagen solubility, and tenderness of beef longissimus lumborum steaks. J Anim Sci. 2017 Mar;95(3):1219-1231. doi: 10.2527/jas.2016.1263. PubMed PMID: 28380530.

4: Smith DJ, Shelver WL, Marx A. Detection of residues in urine and tissues of sheep treated with trace levels of dietary ractopamine HCl. J Anim Sci. 2016 Dec;94(12):5423-5433. doi: 10.2527/jas.2016-0899. PubMed PMID: 28046138.

5: Feldpausch JA, Amachawadi RG, Tokach MD, Scott HM, Nagaraja TG, Dritz SS, Goodband RD, Woodworth JC, DeRouchey JM. Effects of dietary copper, zinc, and ractopamine hydrochloride on finishing pig growth performance, carcass characteristics, and antimicrobial susceptibility of enteric bacteria. J Anim Sci. 2016 Aug;94(8):3278-3293. PubMed PMID: 27695810.

6: Noel JA, Broxterman RM, McCoy GM, Craig JC, Phelps KJ, Burnett DD, Vaughn MA, Barstow TJ, O'Quinn TG, Woodworth JC, DeRouchey JM, Rozell TG, Gonzalez JM. Use of electromyography to detect muscle exhaustion in finishing barrows fed ractopamine HCl. J Anim Sci. 2016 Jun;94(6):2344-56. doi: 10.2527/jas.2016-0398. PubMed PMID: 27285911.

7: Burnett DD, Paulk CB, Tokach MD, Nelssen JL, Vaughn MA, Phelps KJ, Dritz SS, DeRouchey JM, Goodband RD, Haydon KD, Gonzalez JM. Effects of Added Zinc on Skeletal Muscle Morphometrics and Gene Expression of Finishing Pigs Fed Ractopamine-HCL. Anim Biotechnol. 2016;27(1):17-29. doi: 10.1080/10495398.2015.1069301. PubMed PMID: 26634949.

8: Garbossa CA, Carvalho Júnior FM, Silveira H, Faria PB, Schinckel AP, Abreu ML, Cantarelli VS. Effects of ractopamine and arginine dietary supplementation for sows on growth performance and carcass quality of their progenies. J Anim Sci. 2015 Jun;93(6):2872-84. doi: 10.2527/jas.2014-8824. PubMed PMID: 26115274.

9: Pilcher CM, Arentson R, Patience JF. The interaction of fiber, supplied by distillers dried grains with solubles, with an antimicrobial and a nutrient partitioning agent on nitrogen balance, water utilization, and energy digestibility in finishing pigs. J Anim Sci. 2015 Mar;93(3):1124-32. doi: 10.2527/jas.2013-7309. PubMed PMID: 26020889.

10: Paulk CB, Mckinny LJ, Hancock JD, Williams SM, Issa S, Gugle TL. Effects of diet mix time and ractopamine hydrochloride on finishing pig growth and carcass performance. J Anim Sci. 2015 Apr;93(4):1689-94. doi: 10.2527/jas.2014-8379. PubMed PMID: 26020190.

11: Paulk CB, Burnett DD, Tokach MD, Nelssen JL, Dritz SS, DeRouchey JM, Goodband RD, Hill GM, Haydon KD, Gonzalez JM. Effect of added zinc in diets with ractopamine hydrochloride on growth performance, carcass characteristics, and ileal mucosal inflammation mRNA expression of finishing pigs. J Anim Sci. 2015 Jan;93(1):185-96. doi: 10.2527/jas.2014-8286. PubMed PMID: 25568367.

12: Suo D, Zhao G, Wang R, Su X. Determination of ractopamine in animal hair: application to residue depletion in sheep and residue monitoring. J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Dec 1;972:124-8. doi: 10.1016/j.jchromb.2014.09.044. Epub 2014 Oct 8. PubMed PMID: 25444547.

13: Graham AB, Goodband RD, Tokach MD, Dritz SS, DeRouchey JM, Nitikanchana S. The interactive effects of high-fat, high-fiber diets and ractopamine HCl on finishing pig growth performance, carcass characteristics, and carcass fat quality. J Anim Sci. 2014 Oct;92(10):4585-97. doi: 10.2527/jas.2013-7434. PubMed PMID: 25267998.

14: Frobose HL, Dritz SS, Tokach MD, Prusa KJ, DeRouchey JM, Goodband RD, Nelssen JL. Effects of preslaughter feed withdrawal time on finishing pig carcass, body weight gain, and food safety characteristics in a commercial environment. J Anim Sci. 2014 Aug;92(8):3693-700. doi: 10.2527/jas.2013-7367. Epub 2014 Jul 1. PubMed PMID: 24987068.

15: Paulk CB, Tokach MD, Nelssen JL, Burnett DD, Vaughn MA, Phelps KJ, Dritz SS, Derouchey JM, Goodband RD, Woodworth JC, Houser TA, Haydon KD, Gonzalez JM. Effect of dietary zinc and ractopamine hydrochloride on pork chop muscle fiber type distribution, tenderness, and color characteristics. J Anim Sci. 2014 May;92(5):2325-35. doi: 10.2527/jas.2013-7318. Epub 2014 Mar 26. PubMed PMID: 24671591.

16: Arp TS, Howard ST, Woerner DR, Scanga JA, McKenna DR, Kolath WH, Chapman PL, Tatum JD, Belk KE. Effects of dietary ractopamine hydrochloride and zilpaterol hydrochloride supplementation on performance, carcass traits, and carcass cutability in beef steers. J Anim Sci. 2014 Feb;92(2):836-43. doi: 10.2527/jas.2013-7122. PubMed PMID: 24664571.

17: Bohrer BM, Kyle JM, Little KL, Zerby HN, Boler DD. The effects of a step-up ractopamine feeding program on growth performance and low-sodium ham characteristics of purebred Berkshire pigs. J Anim Sci. 2013 Nov;91(11):5535-43. doi: 10.2527/jas.2013-6854. Epub 2013 Sep 17. PubMed PMID: 24045496.

18: Talton CS, Stelzleni AM, Shook JS, Hill GM, Kerth CR, Pence M, Pringle TD. Effects of ovariectomization and ractopamine hydrochloride inclusion on heifer feedlot performance, meat yield, and tenderness of select muscles. Meat Sci. 2014 Jan;96(1):73-81. doi: 10.1016/j.meatsci.2013.06.016. Epub 2013 Jun 15. PubMed PMID: 23896139.

19: James BW, Tokach MD, Goodband RD, Nelssen JL, Dritz SS, Owen KQ, Woodworth JC, Sulabo RC. Effects of dietary L-carnitine and ractopamine HCl on the metabolic response to handling in finishing pigs. J Anim Sci. 2013 Sep;91(9):4426-39. doi: 10.2527/jas.2011-4411. Epub 2013 Jul 12. PubMed PMID: 23851996.

20: James BW, Tokach MD, Goodband RD, Nelssen JL, Dritz SS, Owen KQ, Woodworth JC, Sulabo RC. Interactive effects of dietary ractopamine HCl and L-carnitine on finishing pigs: I. Growth performance. J Anim Sci. 2013 Jul;91(7):3265-71. doi: 10.2527/jas.2011-4286. Epub 2013 May 8. PubMed PMID: 23658355.