WARNING: This product is for research use only, not for human or veterinary use.
Hodoodo CAT#: H562370
CAS#: 856095-68-6
Description: OBA-09 is a neuroprotective agent. It acts by preventing lipid peroxidation, ROS production and causing the recovery of NAD and ATP concentrations to near basal levels.
Hodoodo Cat#: H562370
Name: OBA-09
CAS#: 856095-68-6
Chemical Formula: C10H8O5
Exact Mass: 208.04
Molecular Weight: 208.169
Elemental Analysis: C, 57.70; H, 3.87; O, 38.43
Synonym: OBA-09; OBA 09; OBA09;
IUPAC/Chemical Name: O-Pyruvoylsalicylic acid
InChi Key: ULWCDKMLERRCJA-UHFFFAOYSA-N
InChi Code: InChI=1S/C10H8O5/c1-6(11)10(14)15-8-5-3-2-4-7(8)9(12)13/h2-5H,1H3,(H,12,13)
SMILES Code: O=C(O)C1=CC=CC=C1OC(C(C)=O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
More Info:
Biological target: | |
In vitro activity: | |
In vivo activity: |
The following data is based on the product molecular weight 208.17 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Formulation protocol: | |
In vitro protocol: | |
In vivo protocol: |
1: Rigolin MSM, de Avila ED, Basso FG, Hebling J, de S Costa CA, Mollo Junior FA. Effect of different implant abutment surfaces on OBA-09 epithelial cell adhesion. Microsc Res Tech. 2017 Dec;80(12):1304-1309. doi: 10.1002/jemt.22941. Epub 2017 Aug 30. PubMed PMID: 28856765.
2: Lee HK, Kim SW, Jin Y, Kim ID, Park JY, Yoon SH, Lee JK. Anti-inflammatory effects of OBA-09, a salicylic acid/pyruvate ester, in the postischemic brain. Brain Res. 2013 Aug 28;1528:68-79. doi: 10.1016/j.brainres.2013.06.026. Epub 2013 Jul 11. PubMed PMID: 23850644.
3: Kim SW, Kim HJ, Shin JH, Kim ID, Lee JE, Han PL, Yoon SH, Lee JK. Robust protective effects of a novel multimodal neuroprotectant oxopropanoyloxy benzoic acid (a salicylic acid/pyruvate ester) in the postischemic brain. Mol Pharmacol. 2011 Feb;79(2):220-8. doi: 10.1124/mol.110.067520. Epub 2010 Oct 29. PubMed PMID: 21036874.