1,4-DPCA
featured

    WARNING: This product is for research use only, not for human or veterinary use.

Hodoodo CAT#: H562547

CAS#: 331830-20-7

Description: 1,4-DPCA is a potent and selective inhibitor of prolyl 4-hydroxylase.

Chemical Structure

img
1,4-DPCA
CAS# 331830-20-7
Instruction

Theoretical Analysis

Hodoodo Cat#: H562547
Name: 1,4-DPCA
CAS#: 331830-20-7
Chemical Formula: C13H8N2O3
Exact Mass: 240.05
Molecular Weight: 240.218
Elemental Analysis: C, 65.00; H, 3.36; N, 11.66; O, 19.98

Price and Availability

Size Price Availability Quantity
5mg USD 190 2 Weeks
10mg USD 320 2 Weeks
25mg USD 610 2 Weeks
Bulk inquiry

Synonym: 1,4-DPCA; 1,4 DPCA; 1,4DPCA;

IUPAC/Chemical Name: 4-oxo-1,4-dihydro-1,10-phenanthroline-3-carboxylic acid

InChi Key: XZZHOJONZJQARN-UHFFFAOYSA-N

InChi Code: InChI=1S/C13H8N2O3/c16-12-8-4-3-7-2-1-5-14-10(7)11(8)15-6-9(12)13(17)18/h1-6H,(H,15,16)(H,17,18)

SMILES Code: O=C(C(C(O)=O)=CN1)C2=C1C3=C(C=C2)C=CC=N3

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 240.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Zhang Y, Strehin I, Bedelbaeva K, Gourevitch D, Clark L, Leferovich J, Messersmith PB, Heber-Katz E. Drug-induced regeneration in adult mice. Sci Transl Med. 2015 Jun 3;7(290):290ra92. doi: 10.1126/scitranslmed.3010228. PubMed PMID: 26041709; PubMed Central PMCID: PMC4687906.

2: Xiong G, Deng L, Zhu J, Rychahou PG, Xu R. Prolyl-4-hydroxylase α subunit 2 promotes breast cancer progression and metastasis by regulating collagen deposition. BMC Cancer. 2014 Jan 2;14:1. doi: 10.1186/1471-2407-14-1. PubMed PMID: 24383403; PubMed Central PMCID: PMC3880410.

3: Love RJ, Jones KS. Transient inhibition of connective tissue infiltration and collagen deposition into porous poly(lactic-co-glycolic acid) discs. J Biomed Mater Res A. 2013 Dec;101(12):3599-606. doi: 10.1002/jbm.a.34648. Epub 2013 Jun 14. PubMed PMID: 23766241.